Protein Alignment Oatp30B and slco2b1

DIOPT Version :10

• Sequence 1: NP_609293.2
• Gene: Oatp30B / 34268
• FlyBaseID: FBgn0032123
• Length: 1197
• Species: Drosophila melanogaster
• Sequence 2: XP_031751477.1
• Gene: slco2b1 / 100125037
• XenbaseID: XB-GENE-6046634
• Length: 663
• Species: Xenopus tropicalis
• Alignment Length: 716
• Identity: 235/716 - (32%)
• Similarity: 364/716 - (50%)
• Gaps: 114/716 - (15%)

  Fly   158 CRPYGIQRFARIKIFVVLLSLLVMMQQALSSGYINSVITTIEKRFEIPSSYSGLIASSYEIGNVI 222
            |.|     |..||:||:....| .:.|.|.|||:.|.|:||||||.|.|..||:::|..||||.:
 Frog    29 CHP-----FNNIKVFVLCHGFL-QLSQLLLSGYLRSSISTIEKRFGISSQTSGILSSFNEIGNTV 87

  Fly   223 TVIFVSYLGSRRHIPVWIGIGAVIMGIGSLVFMVPHFTGEP---NPGIAIVNKTSDNICKSALVR 284
            .::||||.|||.|.|.:||.||:|:.....:..:|||...|   :..:|.:.....:||
 Frog    88 LIVFVSYFGSRVHRPRFIGCGAIIVCAAGFLMSLPHFIMGPYEYDKSVASLLSNVTDIC------ 146

  Fly   285 DQDMDLGRLSSGLSNQPLAP-HTLREDNCLEG--KASTTGPVLLFVLAQLLLGCGGSPLFTLGTT 346
                           ||..| .:...|.|:||  ||:.....:|| |.|:|||.|..|:...|.:
 Frog   147 ---------------QPNGPIKSSDNDQCVEGVQKANKNVLFILF-LGQILLGIGSVPIQPFGIS 195

  Fly   347 YVDDHVRTESSSMYIGFMYSMGAFGPVVGFLLGAYLLSFH--MDSLSSTTISITPGDRRWVGMWW 409
            |:||.....:|.:|||.::::...||.|.|:||:.:|.|:  :|.||:..|::||.|.||:|.||
 Frog   196 YIDDFASKRNSPLYIGILFAVTVMGPGVAFILGSAMLRFYVDIDKLSADEITLTPKDPRWIGAWW 260

  Fly   410 GGFLLCGVILLVVAVPFFSFPKVLAR----EKKKIRKSSVVQPVLPNNSRATVATDEMGKVKKLE 470
            .|:|:.|.::.:.::|:|.||:.:.:    ||.:..|.|::              ||
 Frog   261 LGYLVAGSVVAIASIPYFIFPREMPKQGPSEKPEEPKPSLM--------------DE-------- 303

  Fly   471 IVAVTSKEDQSQAPPKVDTGYGKDIKDIPQSMLRLVKNPVYIVTCLGACMELMIVSGFVVFLPKY 535
               :.||.::::     .....:.||..|:.:.|.|||||:|:..|.......:|.|...|:.|:
 Frog   304 ---IKSKTEENE-----KLTLSQFIKVFPKVLFRTVKNPVFILIVLAQGNMSAMVCGLATFMAKF 360

  Fly   536 LETQFSLGKSQANIFTGSIAVPGACIGIFLGGCILKRFQLKPKGAVQFVLITNVICLACYAMLFF 600
            ||.|||:..|.||:..||..:|.|..||.|||.|:||.:|.||.:....:|..:||:.....|.|
 Frog   361 LERQFSITASLANLLIGSANIPAAMSGIVLGGIIMKRHRLTPKQSALMCVIGLIICIFTAIPLVF 425

  Fly   601 LGCDNLKMAGTTIPYYTSNKHGSTLEQPFQVNLTAACNFGCECLTSEVEPVCGNNGLTYFSPCHA 665
            |||...:.|...:.:..|:.....:.:         |:.||:|.::...||||.:|:.|.|||:|
 Frog   426 LGCSTQQFASPRMDHQGSSGIWQNVSE---------CSGGCQCSSAAFNPVCGTDGVEYISPCYA 481

  Fly   666 GCTAF----SSTSNTNYTNCACVRANISSSIYRGAGGSQAQALSANENFAEVTVVPVATAGPCAT 726
            ||.|.    |.|...|||.|.|:          .|.||                   |..|.|.|
 Frog   482 GCGAVQFGESPTEVLNYTRCTCI----------PAAGS-------------------AKPGSCGT 517

  Fly   727 PC-RTIYPFLILLFFMTFLVASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPILFGN 790
            .| :.:.||::|......|.:..|.|..|::||||...::|.|:|:||::.|:..::|.|:::|:
 Frog   518 VCGQLLVPFMVLSCLAGGLASMAQTPSFMLILRSVKPTDKSLAIGIQFMLLRILAWLPGPVMYGS 582

  Fly   791 LIDSTCILWKSSCGEKGGRCLIYDIEKFRYKYVGLCASVKLIALVIFMVDWWLVRRRKQLEKMKP 855
            :||||||||...||:|.. |..||....|.:::||....::..|:.|...::::|||:::...|.
 Frog   583 VIDSTCILWGQKCGKKTS-CQYYDNNLLRQRFIGLQILFEIGGLIFFTAVFFVLRRREKVSAEKS 646

  Fly   856 L 856
            :
 Frog   647 M 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp30B	NP_609293.2	MFS_SLCO5_OATP5	170..758	CDD:340962	195/604 (32%)
		UhpC	<730..795	CDD:441872	22/64 (34%)
slco2b1	XP_031751477.1	MFS	35..550	CDD:475125	196/605 (32%)