DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gdi and gdi1

DIOPT Version :9

Sequence 1:	NP_001245953.1	Gene:	Gdi / 34264	FlyBaseID:	FBgn0004868	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_001018444.2	Gene:	gdi1 / 554985	ZFINID:	ZDB-GENE-050522-504	Length:	447	Species:	Danio rerio

Alignment Length:	448	Identity:	302/448 - (67%)
Similarity:	368/448 - (82%)	Gaps:	6/448 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNEEYDAIVLGTGLKECILSGMLSVSGKKVLHIDRNKYYGGESASITPLEELFQRYGL-EPPGER 64
            |:||||.|||||||.||||||::||:||||||:|||.||||||:||||||||::|:|: :.|.|.
Zfish     1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFGISDSPPES 65

  Fly    65 FGRGRDWNVDLIPKFLMANGQLVKLLIHTGVTRYLEFKSIEGSYVYKGGKIAKVPVDQKEALASD 129
            .|||||||||||||||||||||||:|::|.|||||:||.:|||:|||||||.|||..:.|||||:
Zfish    66 MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASN 130

  Fly   130 LMGMFEKRRFRNFLIYVQDFREDDPKTWKDFDPTKANMQGLYDKFGLDKNTQDFTGHALALFRDD 194
            |||||||||||.||::|.:|.|:||||::..||....|..:|.||.|.::..|||||||||:|.|
Zfish   131 LMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPKLTTMGEVYKKFDLGQDVIDFTGHALALYRTD 195

  Fly   195 EYLNEPAVNTIRRIKLYSDSLARYGKSPYLYPMYGLGELPQGFARLSAIYGGTYMLDKPIDEIVL 259
            :||.:|.:.||.||||||:|||||||||||||:|||||||||||||||||||||||:||:||||:
Zfish   196 DYLEQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDEIVM 260

  Fly   260 GEGGKVVGVRSGEEVAKCKQVYCDPSYVPEKVRKRGKVIRCICILDHPVASTKDGLSTQIIIPQK 324
             |||.||||:|..:||:|||:.|||||:||:|.|.|:|:|.||:|.||:.:|.|..|.||||||.
Zfish   261 -EGGHVVGVKSEGQVARCKQLICDPSYIPERVHKVGQVVRVICVLSHPIKNTNDANSCQIIIPQN 324

  Fly   325 QVGRKSDIYVSLVSSTHQVAAKGWFVGMVSTTVETENPEVEIKPGLDLLEPIAQKFVTISDYLEP 389
            ||.|||||||.::|..|.|||:|.::.:|||||||.:||.||:|.|:|||||.||||.|||..||
Zfish   325 QVNRKSDIYVCMISYAHNVAAQGKYIAIVSTTVETSDPEAEIEPALELLEPIDQKFVAISDMYEP 389

  Fly   390 IDDGSESQIFISESYDATTHFETTCLDVLNIFKRGTGETFDFSKIKHE----LGDEEQ 443
            .|||:|||:|.|.||||||||||||.|:.:|:||.||..|||..:|.:    .|::||
Zfish   390 TDDGTESQVFASRSYDATTHFETTCNDIKDIYKRMTGSDFDFENMKRKQNDVFGEDEQ 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gdi	NP_001245953.1	GDI	1..435	CDD:279353	298/434 (69%)
gdi1	NP_001018444.2	GDI	1..436	CDD:279353	298/435 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585543
Domainoid	1	1.000	616	1.000	Domainoid score	I179
eggNOG	1	0.900	-	-		E1_COG5044
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37487
Inparanoid	1	1.050	620	1.000	Inparanoid score	I853
OMA	1	1.010	-	-		QHG53557
OrthoDB	1	1.010	-	-		D388394at33208
OrthoFinder	1	1.000	-	-		FOG0001483
OrthoInspector	1	1.000	-	-		otm25948
orthoMCL	1	0.900	-	-		OOG6_100967
Panther	1	1.100	-	-	O	PTHR11787
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R485
SonicParanoid	1	1.000	-	-		X942
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800