DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gdi and Gdi1

DIOPT Version :9

Sequence 1:	NP_001245953.1	Gene:	Gdi / 34264	FlyBaseID:	FBgn0004868	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_034403.1	Gene:	Gdi1 / 14567	MGIID:	99846	Length:	447	Species:	Mus musculus

Alignment Length:	441	Identity:	300/441 - (68%)
Similarity:	365/441 - (82%)	Gaps:	2/441 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNEEYDAIVLGTGLKECILSGMLSVSGKKVLHIDRNKYYGGESASITPLEELFQRYG-LEPPGER 64
            |:||||.|||||||.||||||::||:||||||:|||.||||||:||||||||::|:. ||.|.|.
Mouse     1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQILEGPPES 65

  Fly    65 FGRGRDWNVDLIPKFLMANGQLVKLLIHTGVTRYLEFKSIEGSYVYKGGKIAKVPVDQKEALASD 129
            .|||||||||||||||||||||||:|::|.|||||:||.:|||:|||||||.|||..:.|||||:
Mouse    66 MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASN 130

  Fly   130 LMGMFEKRRFRNFLIYVQDFREDDPKTWKDFDPTKANMQGLYDKFGLDKNTQDFTGHALALFRDD 194
            |||||||||||.||::|.:|.|:||||::..||...:|:.:|.||.|.::..|||||||||:|.|
Mouse   131 LMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQDVIDFTGHALALYRTD 195

  Fly   195 EYLNEPAVNTIRRIKLYSDSLARYGKSPYLYPMYGLGELPQGFARLSAIYGGTYMLDKPIDEIVL 259
            :||::|.:.||.||||||:|||||||||||||:|||||||||||||||||||||||:||:|:|::
Mouse   196 DYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIM 260

  Fly   260 GEGGKVVGVRSGEEVAKCKQVYCDPSYVPEKVRKRGKVIRCICILDHPVASTKDGLSTQIIIPQK 324
             |.||||||:|..|||:|||:.|||||:|::|:|.|:|||.||||.||:.:|.|..|.||||||.
Mouse   261 -ENGKVVGVKSEGEVARCKQLICDPSYIPDRVQKAGQVIRIICILSHPIKNTNDANSCQIIIPQN 324

  Fly   325 QVGRKSDIYVSLVSSTHQVAAKGWFVGMVSTTVETENPEVEIKPGLDLLEPIAQKFVTISDYLEP 389
            ||.|||||||.::|..|.|||:|.::.:.||||||..||.|::|.|:|||||.||||.|||..||
Mouse   325 QVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETAEPEKEVEPALELLEPIDQKFVAISDLYEP 389

  Fly   390 IDDGSESQIFISESYDATTHFETTCLDVLNIFKRGTGETFDFSKIKHELGD 440
            ||||||||:|.|.||||||||||||.|:.:|:||..|..|||..:|.:..|
Mouse   390 IDDGSESQVFCSCSYDATTHFETTCNDIKDIYKRMAGSAFDFENMKRKQND 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gdi	NP_001245953.1	GDI	1..435	CDD:279353	298/434 (69%)
Gdi1	NP_034403.1	GDI	1..436	CDD:279353	298/435 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841038
Domainoid	1	1.000	614	1.000	Domainoid score	I188
eggNOG	1	0.900	-	-		E1_COG5044
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37487
Inparanoid	1	1.050	618	1.000	Inparanoid score	I886
Isobase	1	0.950	-	0.930827	Normalized mean entropy	S274
OMA	1	1.010	-	-		QHG53557
OrthoDB	1	1.010	-	-		D388394at33208
OrthoFinder	1	1.000	-	-		FOG0001483
OrthoInspector	1	1.000	-	-		otm43108
orthoMCL	1	0.900	-	-		OOG6_100967
Panther	1	1.100	-	-	O	PTHR11787
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R485
SonicParanoid	1	1.000	-	-		X942
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750