Protein Alignment Gdi and CHM

DIOPT Version :9

• Sequence 1: NP_001245953.1
• Gene: Gdi / 34264
• FlyBaseID: FBgn0004868
• Length: 443
• Species: Drosophila melanogaster
• Sequence 2: NP_000381.1
• Gene: CHM / 1121
• HGNCID: 1940
• Length: 653
• Species: Homo sapiens
• Alignment Length: 558
• Identity: 125/558 - (22%)
• Similarity: 195/558 - (34%)
• Gaps: 208/558 - (37%)

  Fly     4 EYDAIVLGTGLKECILSGMLSVSGKKVLHIDRNKYYGGESASI---------------------- 46
            |:|.||:||||.|.|::...|.||::|||:|...||||..||.
Human     8 EFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLKEYQENSDIVSDS 72

  Fly    47 ----------------------------------------------------------------- 46
                                                                             
Human    73 PVWQDQILENEEAIALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQKNHALVTSANSTEAADSA 137

  Fly    47 --------------------TPL---EELFQRYGLEPPGER------------------------ 64
                                ||.   |...:..|.|..||:
Human   138 FLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKENHCDDKTCVPSTSAEDMSENVPI 202

  Fly    65 ------------------FGRGRDWNVDLIPKFLMANGQLVKLLIHTGVTRYLEFKSIEGSYVYK 111
                              ...||.:|:||:.|.|.:.|.|:.|||.:.|:||.|||:|.....::
Human   203 AEDTTEQPKKNRITYSQIIKEGRRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFR 267

  Fly   112 GGKIAKVPVDQKEALASDLMGMFEKRRFRNFLIYVQDFREDDPKTWKDFDPTKANMQGLYDKFGL 176
            .|::.:||..:.:...|..:.|.|||....||.:..:: |..|..:|.::...     .|:....
Human   268 EGRVEQVPCSRADVFNSKQLTMVEKRMLMKFLTFCMEY-EKYPDEYKGYEEIT-----FYEYLKT 326

  Fly   177 DK---NTQDFTGHALALFRDDEYLNEPAVNTI---RRIKLYSDSLARYGKSPYLYPMYGLGELPQ 235
            .|   |.|....|::|:      .:|.|.:||   :..|.:...|.|||.:|:|:|:||.|||||
Human   327 QKLTPNLQYIVMHSIAM------TSETASSTIDGLKATKNFLHCLGRYGNTPFLFPLYGQGELPQ 385

  Fly   236 GFARLSAIYGGTYMLDKPIDEIVLGEGGKVVGVRSGEEVAKCKQV-------------YCDPSYV 287
            .|.|:.|::||.|.|...:..:|:           .:|..|||.:             ..:.||.
Human   386 CFCRMCAVFGGIYCLRHSVQCLVV-----------DKESRKCKAIIDQFGQRIISEHFLVEDSYF 439

  Fly   288 PEKVRKR---GKVIRCICILDHPVASTKDGLSTQII-IPQKQVGRKSDIYVSLVSSTHQVAAKGW 348
            ||.:..|   .::.|.:.|.|..|..|.......|: :|.::.|..:...:.|.|||.......:
Human   440 PENMCSRVQYRQISRAVLITDRSVLKTDSDQQISILTVPAEEPGTFAVRVIELCSSTMTCMKGTY 504

  Fly   349 FVGMVSTTVETENPEVEIKPGLDLLEPIAQK-FVTISD 385
            .|.:..|:.:|...:         ||.:.|| ||..::
Human   505 LVHLTCTSSKTARED---------LESVVQKLFVPYTE 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdi	NP_001245953.1	GDI	1..435	CDD:279353	125/558 (22%)
CHM	NP_000381.1	NAD_binding_8	13..>54	CDD:290186	20/40 (50%)
		NADB_Rossmann	225..542	CDD:304358	94/341 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	606..653

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810