| Sequence 1: | NP_001260291.1 | Gene: | numb / 34263 | FlyBaseID: | FBgn0002973 | Length: | 556 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_005447.1 | Gene: | MAPK8IP1 / 9479 | HGNCID: | 6882 | Length: | 711 | Species: | Homo sapiens |
| Alignment Length: | 242 | Identity: | 55/242 - (22%) |
|---|---|---|---|
| Similarity: | 94/242 - (38%) | Gaps: | 65/242 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 GNSSSHTHEPLERGFTRGKFGDVKNGKS------ASFRFSKKSPKKMD----------------- 43
Fly 44 ----RLRRSFRDSF--------RRRKDRVPESSKPHQWQADEEAVRSATCSFSVKYLGCVEVFES 96
Fly 97 RGMQVCEEALKVLRQSRR------RPVRGLLHVSGDGLRV---VDD--ETKGLIVDQ--TIEKVS 148
Fly 149 FCAPDRNHERGFSYICRDGTTRRWMCHGFLACKDSGERLSHAVGCAF 195 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| numb | NP_001260291.1 | PTB_Numb | 67..201 | CDD:241298 | 39/142 (27%) |
| NumbF | 269..374 | CDD:283874 | |||
| MAPK8IP1 | NP_005447.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..27 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 78..371 | ||||
| JNK-binding domain (JBD) | 127..285 | ||||
| Minimal inhibitory domain (MID) | 157..176 | ||||
| Interaction with MAP3K7. /evidence=ECO:0000269|PubMed:17709393 | 283..471 | 2/3 (67%) | |||
| D-box 1 | 353..360 | ||||
| D-box 2 | 364..372 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 429..451 | ||||
| Interaction with VRK2. /evidence=ECO:0000269|PubMed:18286207 | 471..660 | 41/204 (20%) | |||
| SH3_JIP1 | 492..546 | CDD:212876 | 7/53 (13%) | ||
| PTB_JIP | 563..711 | CDD:269923 | 39/140 (28%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165141127 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.840 | |||||