Sequence 1: | NP_001260291.1 | Gene: | numb / 34263 | FlyBaseID: | FBgn0002973 | Length: | 556 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_004747.1 | Gene: | NUMBL / 9253 | HGNCID: | 8061 | Length: | 609 | Species: | Homo sapiens |
Alignment Length: | 555 | Identity: | 217/555 - (39%) |
---|---|---|---|
Similarity: | 272/555 - (49%) | Gaps: | 141/555 - (25%) |
- Green bases have known domain annotations that are detailed below.
Fly 42 MDRLRRSFRDSFRRRKDRVPESSKPHQWQADEEAVRSATCSFSVKYLGCVEVFESRGMQVCEEAL 106
Fly 107 KVLRQSRRRPVRGLLHVSGDGLRVVDDETKGLIVDQTIEKVSFCAPDRNHERGFSYICRDGTTRR 171
Fly 172 WMCHGFLACKDSGERLSHAVGCAFAVCLERKQRRDKECGVTMTFDTKNSTFTRTGSFR------- 229
Fly 230 ------QQTLTERLAMATVGTNERSVDGPGSAMPG---PPAATVKP-------------FNPFAI 272
Fly 273 ERPHATPNMLERQSSFRLSTIGSQ--SPFKRQMSLRINDLPSNADRQRAFLTAAAGNPMQTPLRS 335
Fly 336 VSPIAEVSPAKSAGADPLSAAAVAADSVSQLCQELSQGLSLLTQTDALLAAGEDLNFNNNRSINQ 400
Fly 401 NIIAAEKQVQHVHSYAPPTA----------QVTPRVASTTPTYQTLHSQSPSRSEQSIETSTELP 455
Fly 456 NAEQWLGHVVRSTSPAAPKRPTYLANVGRAQTLASGT---GAAVGGGGPDDPFDAEWVANVAAAK 517
Fly 518 QLSPDLPIPSTARSPLARHSTNPFISPPKAPAQSF 552 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
numb | NP_001260291.1 | PTB_Numb | 67..201 | CDD:241298 | 100/133 (75%) |
NumbF | 269..374 | CDD:283874 | 36/106 (34%) | ||
NUMBL | NP_004747.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..68 | 15/28 (54%) | |
PTB_Numb | 64..198 | CDD:241298 | 100/133 (75%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 223..283 | 17/67 (25%) | |||
NumbF | 287..371 | CDD:283874 | 36/106 (34%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 372..421 | 14/86 (16%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 434..464 | 3/29 (10%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 537..609 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165141148 | |
Domainoid | 1 | 1.000 | 191 | 1.000 | Domainoid score | I3250 |
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 1 | 1.050 | 320 | 1.000 | Inparanoid score | I2533 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D1110016at2759 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0003748 | |
OrthoInspector | 1 | 1.000 | - | - | otm41487 | |
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR11232 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2695 |
SonicParanoid | 1 | 1.000 | - | - | X2613 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
11 | 11.030 |