Protein Alignment numb and nos1apa

DIOPT Version :10

• Sequence 1: NP_523523.2
• Gene: numb / 34263
• FlyBaseID: FBgn0002973
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: XP_021332861.1
• Gene: nos1apa / 553539
• ZFINID: ZDB-GENE-081024-1
• Length: 505
• Species: Danio rerio
• Alignment Length: 507
• Identity: 111/507 - (21%)
• Similarity: 189/507 - (37%)
• Gaps: 121/507 - (23%)

  Fly    72 DEEAVRSATCSFSVKYLGCVEVFESRGMQVCEEALKVLRQS------RRRPVRGLLHVSGDGLRV 130
            :|||.:.. .:|..||:|.::|...........|::.:|..      :::.|.  :.||.||::|
Zfish    22 NEEAFQHG-INFEAKYIGSLDVARPNSRVEIVAAMRRIRYEFKVKNIKKKKVN--IIVSVDGVKV 83

  Fly   131 -----------VDDETKGLIVDQTIEKVSFCAPDRNHERGFSYICRDGTTRRWMCHGFLACKDS- 183
                       ..||:|.:::...|.::.:.:.|....:.||||.|||.:..:.|:.|.:.|.|
Zfish    84 ALRKKKKKKEWTWDESKMMVMQDPIYRIFYVSHDSQDLKIFSYIARDGQSNVFRCNVFKSKKKSQ 148

  Fly   184 GERLSHAVGCAFAVC----LERKQRR---------DKECGVTMTFDTKNSTFTRTG-SFRQQTLT 234
            ..|:...||.||.||    |:..|:.         ||.|             |.:| :.|:.|..
Zfish   149 AMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGDADKTC-------------TDSGVAGRELTGA 200

  Fly   235 ERLAMATVGTNERSVDGPGSAMPGPPAATVKPFNPFAIE--------------RPHATPNMLERQ 285
            |:.|     .:|..:|.....:|.   :|:..|:....:              :|...|.:|...
Zfish   201 EKPA-----ADETDIDAEELPLPD---STMDEFSRGVTDLDAAKKDEDVSKDKKPSEEPVILLAS 257

  Fly   286 SSFRLSTIGSQSPFKRQMSL--RINDLPSNADRQRAFLTAAAGNPMQTPLRSVSPIAEVSPAKSA 348
            ....|.: ||..|....:|:  ::..|.....:|:          .||.:    .:|:|...|
Zfish   258 PKLLLPS-GSDLPSSTPLSVHHQLQLLQQQLTQQQ----------QQTQV----AVAQVHLLK-- 305

  Fly   349 GADPLSA-AAVAADSVSQLCQELSQGLSLLTQTDALLAAGEDLNFNNNRSINQNIIAAEKQVQHV 412
              |.||| ||...::.:::.|.|.|...||.....|:...::|..   :...|..:.::..:..:
Zfish   306 --DQLSAEAAARIEAQARVHQLLLQNKDLLQHISLLVKQIQELEL---KLAGQGSMGSQDSLLEI 365

  Fly   413 --HSYAPPTA--QVTPRVA-STTP-----TYQTLHSQSPSRSEQSI---ETSTELPNAEQWLGHV 464
              .:..||..  ..|||.. |..|     |..:|...||...:|.:   |....||...    |.
Zfish   366 TFRANVPPVLCDPSTPRPEDSILPPLNDGTQLSLPLCSPIGRDQGLIKFECFRFLPGPP----HQ 426

  Fly   465 VRSTSPAAPKRPTYLANVGRAQTLAS-------GTGAAVGGGGPDDPFDAEW 509
            ....||..|.:.  :::..|.:.|.|       .:|.|.......|..|..|
Zfish   427 QEEDSPDTPSQD--VSSSSRDELLGSLELLRFRESGIASEYESNTDESDESW 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
numb	NP_523523.2	PTB_Numb	67..201	CDD:241298	40/150 (27%)
		NumbF	269..374	CDD:461874	24/121 (20%)
nos1apa	XP_021332861.1	PTB_CAPON-like	2..180	CDD:269968	41/160 (26%)