Protein Alignment numb and CG42673

DIOPT Version :9

• Sequence 1: NP_001260291.1
• Gene: numb / 34263
• FlyBaseID: FBgn0002973
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_729510.1
• Gene: CG42673 / 39111
• FlyBaseID: FBgn0261555
• Length: 904
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 127/688 - (18%)
• Similarity: 184/688 - (26%)
• Gaps: 304/688 - (44%)

  Fly    22 GDVKNGKSASFRFSK-------KSPKKMDRL-----RRSFRDSFRRRKD---------------- 58
            |||   ..|..:|.:       .||:.:.|.     |...|...:|||.
  Fly   203 GDV---LKARLKFKRLPGDHYEASPEALRRAHLLHQRSEQRHQLQRRKSLSDQQSSSSLSSGGGG 264

  Fly    59 ----------RVPESSKPHQWQADEEAVRSATCSFSVKYLGCVEVFESRGMQVCEEALKVLRQSR 113
                      ..|::.||.:..:..|.:.:                   |.|:....|...||:|
  Fly   265 GGNANGSIMLERPKTDKPRKKLSFREPIIA-------------------GDQILPLILSEQRQAR 310

  Fly   114 RRPVRGLLHVSGDGLRVVDDETKGLIVDQTIEKVSFCAPDRNHERGFSYICRDGTTRRWMCHGFL 178
            :|.....|..|..||.:.|.:.                           :|.:.|.....|
  Fly   311 QRRRSSPLERSRVGLAIADCDN---------------------------LCNNRTKDAISC---- 344

  Fly   179 ACKDS-----GERLSHAVGCAFAVC---------LERKQRRDKECGVTMTFDTKNSTFTRTGSFR 229
            .|..|     ..|:...||.||.||         ||....|.         |..:|.........
  Fly   345 GCATSDPESQAMRIVRTVGQAFEVCHKFNLHKNSLEPNDERS---------DISSSELLDVEQIS 400

  Fly   230 QQTLTERLAMATVGTNERSVDGPGSAMPGPPAATVKP-FNPFAIERPHATPNMLERQSSFRLSTI 293
            :|.|:|        ..||.  |..:..|......:.| .|....:||:.. :::...||.|.|
  Fly   401 EQQLSE--------DGERG--GGDNETPKKEHLAITPDLNHTQPQRPNHL-DIMPSHSSLRKS-- 452

  Fly   294 GSQSPFKRQMSLRINDLPSNADRQRAFLTAAAGNPMQTPLRSVSPIAEVSPAKSAGADPLSAAAV 358
                          |.|..:.|.:      :.|:|.       ||.:|::..|    |.|.|.|:
  Fly   453 --------------NSLLCDVDDK------SPGSPS-------SPRSEITQLK----DQLEAQAL 486

  Fly   359 AADSV--------SQLCQELSQGLSLLTQTDALLAAGEDL------------------------- 390
            .....        .||..|.:..:....:|..||....:|
  Fly   487 QTRQALGQLMLVREQLISETNARIEAQARTQQLLQQNRELLEHLASLGAYNEQQTAGLTSANIGM 551

  Fly   391 ---------------NFNNNRSINQNI-----------------IAAEKQVQHV----------- 412
                           |.||..:|||.|                 ....:|.||:
  Fly   552 APQQSQLQMLLQATSNNNNLATINQQISNLGSINQQLTSLSHQLSGLNQQSQHLQNLQQQQQQQQ 616

  Fly   413 -----HSYAPPTAQVTPRVA---STTPTYQTLHS------------QSPSRSEQSIETSTELPNA 457
                 .:.|.|||...|..|   |..|:...|.|            |..:.|:...:.:.||.|.
  Fly   617 QQQQQQTQAAPTAATPPPAAGGSSPYPSMSALQSISNQLQQQQQQQQQDALSKDLFQVNQELLNR 681

  Fly   458 EQWLGHVVRSTSPAAPKRPTYLANVGRAQTLASGT-------------------GAAVGGGGPDD 503
            .|.|               ...||.|::|...|.|                   ..|.|.||
  Fly   682 LQAL---------------NLNANPGQSQPTPSATAHNSFFYVNPLSCTPATPNNNAGGAGG--- 728

  Fly   504 PFDAEWVANVAAAKQLSPDLPIPSTARSPLARHSTNPF 541
               ..::.:.||...|:|         |||...:.|.|
  Fly   729 ---FNFLTSPAATGTLTP---------SPLGTMNRNSF 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
numb	NP_001260291.1	PTB_Numb	67..201	CDD:241298	26/147 (18%)
		NumbF	269..374	CDD:283874	22/112 (20%)
CG42673	NP_729510.1	PH-like	<352..386	CDD:302622	9/33 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438625
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11232
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940