Protein Alignment numb and fam43a

DIOPT Version :9

• Sequence 1: NP_001260291.1
• Gene: numb / 34263
• FlyBaseID: FBgn0002973
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_999870.1
• Gene: fam43a / 334166
• ZFINID: ZDB-GENE-030131-6098
• Length: 348
• Species: Danio rerio
• Alignment Length: 356
• Identity: 70/356 - (19%)
• Similarity: 132/356 - (37%)
• Gaps: 97/356 - (27%)

  Fly    29 SASFRFSKKSPKK-MDRLRRSFRDSFRRRKDRVPESSKPHQWQADEEAVRSATCSFSVKYLGCVE 92
            ||...|:|..|:. ::|:...|:.  :|:|.:: .|..|               :::|.|||...
Zfish    31 SALTSFAKSCPESALNRVGSMFKS--KRKKVKI-TSEDP---------------TYTVLYLGNAT 77

  Fly    93 VFESRGMQVCEEAL-KVLRQSR--RRPVRGLLHVSGDGLRV--VDDETKGLIVDQTIEKVSFCAP 152
            ..:|:|....:.|: |:..:|.  :...:..|.:|..|:|:  ||::.|.......:.::::|..
Zfish    78 TIQSKGDGCTDVAVSKIWGKSEMGKNGTKMKLTISSQGIRMVHVDEKAKRPGHLYLLHRITYCVA 142

  Fly   153 DRNHERGFSYICRDGTTRRWM---CHGFLACKDSGER----LSHAVGCAFAVCLERKQRRDKECG 210
            |....:.|::|.|.....:.:   ||..|..|....:    |.:..........:|.:|||
Zfish   143 DPRLPKIFAWIYRHEMKHKAVMLRCHAVLVSKPEKAKAMALLLYQTSATALAEFKRLKRRD---- 203

  Fly   211 VTMTFDTKNSTFTRTGSFRQQTLTERLAMATVGTNERSVDGPGSAMPGPPAATVKPFNPFAIERP 275
                 |.::         :||.|.....:..|...:..   .|.....||           :||.
Zfish   204 -----DARH---------QQQQLIGEQTIPLVPLRKLL---NGQCYYKPP-----------VERS 240

  Fly   276 HATPNM------------LERQSSFR----LST----IGSQSPFKRQMSLRINDLPSNADRQRAF 320
            .:.|.:            .|:...|.    |.|    :|:.   |:::...||||.|
Zfish   241 RSAPKLGSITEDLLGEEEEEKAMHFECEDILDTDSDCVGNG---KQELCQIINDLGS-------- 294

  Fly   321 LTAAAGNPMQTPLRSVSPIAEVSPAKSAGAD 351
              ...||.:|| |::...:..:...:|.|::
Zfish   295 --MCIGNDVQT-LKADLRVTRLLSGESTGSE 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
numb	NP_001260291.1	PTB_Numb	67..201	CDD:241298	26/145 (18%)
		NumbF	269..374	CDD:283874	21/103 (20%)
fam43a	NP_999870.1	PID_2	67..252	CDD:258856	41/216 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574060
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840