Protein Alignment numb and Fam43b

DIOPT Version :9

• Sequence 1: NP_001260291.1
• Gene: numb / 34263
• FlyBaseID: FBgn0002973
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: XP_006239356.1
• Gene: Fam43b / 313650
• RGDID: 1560959
• Length: 330
• Species: Rattus norvegicus
• Alignment Length: 273
• Identity: 55/273 - (20%)
• Similarity: 95/273 - (34%)
• Gaps: 80/273 - (29%)

  Fly    42 MDRLRRSFRDSFRRRKDRVPESSKPHQWQADEEAVRSATCSFSVKYLGCVEVFESRGMQVCEEAL 106
            ::||.|.||.  ||:|..:.:...                :::|.|||......::|....::|:
  Rat    49 LERLGRVFRS--RRQKVELNKEDP----------------TYTVWYLGNAVTLHAKGDGCTDDAV 95

  Fly   107 KVLRQSRRRPVRGL---LHVSGDGLRVVDDET-------KGLIVDQTIEKVSFCAPDRNHERGFS 161
            ..: .:|..|..|.   |.:...|:|:...|.       :.......:.::::||.|..|.|.|:
  Rat    96 GRI-WARCGPGGGTKMKLTLGPHGIRMQPSERGSGGSGGRRPAHAYLLPRITYCAADGRHPRVFT 159

  Fly   162 YICRDGTTRRWM---CHGFLACK----DSGERLSHAVGCAFAVCLERKQRRDKECGVTMTFDTKN 219
            ::.|.....:.:   ||..|..:    .|..||.|....|.....:|.||:.         |.::
  Rat   160 WVYRHQARHKAVVLRCHAVLLARAHKARSLARLLHQTALAAFSDFKRLQRQS---------DARH 215

  Fly   220 STFTRTGSFRQQTLTERLAMATVGTNERSVDGPGSAMPGPPAATVK----PFNPFAIERPHATPN 280
                    .|||.|              ...|..:::|..|...:.    .:.|...||....|
  Rat   216 --------VRQQHL--------------RAGGAAASVPRAPLRRLLNAKCAYRPPPGERSRGAP- 257

  Fly   281 MLERQSSFRLSTI 293
                    |||:|
  Rat   258 --------RLSSI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
numb	NP_001260291.1	PTB_Numb	67..201	CDD:241298	28/150 (19%)
		NumbF	269..374	CDD:283874	8/25 (32%)
Fam43b	XP_006239356.1	PH-like	71..262	CDD:418428	46/231 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334816
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840