Protein Alignment numb and nos1apb

DIOPT Version :10

• Sequence 1: NP_523523.2
• Gene: numb / 34263
• FlyBaseID: FBgn0002973
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: XP_021322431.1
• Gene: nos1apb / 100331166
• ZFINID: ZDB-GENE-100824-1
• Length: 422
• Species: Danio rerio
• Alignment Length: 489
• Identity: 100/489 - (20%)
• Similarity: 157/489 - (32%)
• Gaps: 162/489 - (33%)

  Fly    57 KDRVPESSKPHQWQADEEAVRSATCSFSVKYLGCVEVFESRGMQVCEEALKVLRQSRR------- 114
            |..:.:.|...:..||.|.......:|.||::|.:::...:      ..:::|...||
Zfish     6 KYNLVDDSMDQRIPADNEGQFQHGLTFEVKFIGSLDIVRPK------SRIEILAAMRRIRYEFKI 64

  Fly   115 ---RPVRGLLHVSGDGLRVV------------DDETKGLIVDQTIEKVSFCAPDRNHERGFSYIC 164
               :..:..|.||.||::||            .||:...:....|.::.:.:.|....:.||||.
Zfish    65 KNIKKKKVSLIVSVDGVKVVLRKKKKVKFEYSWDESPVTLAQDPIFRIFYVSHDSQDLKIFSYIA 129

  Fly   165 RDGTTRRWMCHGFLA-CKDSGERLSHAVGCAFAVCLERKQRRDKECGVTMTFDTKNSTFTRTGSF 228
            ||..:..:.|:.|.: .|....|:...||.||.||
Zfish   130 RDKKSNVFRCNVFKSKRKSQAMRIVRTVGQAFEVC------------------------------ 164

  Fly   229 RQQTLTERLAMATVGTNERSVDGPGSAMPGPPAATVKPFNPFAIERPHATPNMLERQSSFRLSTI 293
            .:|:|....|....|..|||.|...:|  |.........:|       .|...:|.:|...||
Zfish   165 HKQSLDNADAWLVKGEEERSKDEAVAA--GSSTERAGDADP-------ETDEKVEEESKSPLS-- 218

  Fly   294 GSQSPFKRQMSLRINDLPSNADRQRAFLTAAAGNPMQTPLRSVSPIAEVSPAKSAGADPLSAAAV 358
               ||......:::        .||.|        .|...||.:..|:|...:...:...:|...
Zfish   219 ---SPLSVSHQVQL--------LQRQF--------QQQEQRSHAASAQVVLLQQQLSVETNARTE 264

  Fly   359 AADSVSQLCQ---ELSQGLSLLTQTDALLAAGEDLNFNNNRSINQNIIAAEKQVQHVHSYAPPTA 420
            |...|.||.|   ||.|.||||.                            |.||.:.....|
Zfish   265 AQARVQQLLQQNTELLQHLSLLV----------------------------KHVQELELRTQP-- 299

  Fly   421 QVTPRVASTTPTYQTLHSQSPSRSEQSIETSTELPNAEQWLGHVVRSTSPAAPK--RPTYLANVG 483
                            |..||..|:.|:            |...:|:..||..:  :|..|.:..
Zfish   300 ----------------HKNSPLGSQDSL------------LEIALRANMPAVSREPKPNPLLSAQ 336

  Fly   484 RAQTLASG----------TGAAVGGGGPDDPFDA 507
            |:..|::.          |||:.....|:...|:
Zfish   337 RSFPLSNSLVRLDGFHFFTGASEQEKKPEQDRDS 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
numb	NP_523523.2	PTB_Numb	67..201	CDD:241298	37/156 (24%)
		NumbF	269..374	CDD:461874	25/107 (23%)
nos1apb	XP_021322431.1	PH-like	4..172	CDD:473070	41/201 (20%)