Protein Alignment FucTB and FUT6

DIOPT Version :10

• Sequence 1: NP_609288.4
• Gene: FucTB / 34260
• FlyBaseID: FBgn0032117
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: NP_000141.1
• Gene: FUT6 / 2528
• HGNCID: 4017
• Length: 359
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 79/296 - (26%)
• Similarity: 119/296 - (40%)
• Gaps: 63/296 - (21%)

  Fly    40 PVELVWWSRDMSWNYD---VQRQC-----GIHTCRITNKRSRRPWARGVLFYGSNI---KTGDFP 93
            |:.|:|     :|.::   ...:|     |...|.||..|...|.|..|:.:...:   .:...|
Human    62 PLILLW-----TWPFNKPIALPRCSEMVPGTADCNITADRKVYPQADAVIVHHREVMYNPSAQLP 121

  Fly    94 -LPRNEHQIWALLHEESPRNTPFVSNKEFLRHFHFTSTFSRYSNLPLTTMYLPSGEALTSKDYYV 157
             .||.:.|.|.....|||            .|.........|.|  ||..|....:..|...:..
Human   122 RSPRRQGQRWIWFSMESP------------SHCWQLKAMDGYFN--LTMSYRSDSDIFTPYGWLE 172

  Fly   158 TFDGKSKYGYRPSTS-------VVFLQSDCDTMSGREDYVKELMKHLPIDSYGSCLRNRDLPESL 215
            .:.|:..:   |..:       |.:..|:....|.|..|.:.|..||.:|.||.  .::.||:.
Human   173 PWSGQPAH---PPLNLSAKTELVAWAVSNWGPNSARVRYYQSLQAHLKVDVYGR--SHKPLPQG- 231

  Fly   216 QKDYLNNLYSPELLRFLSEYKFMIAIENAACPDYITEKFWR-PLIMGVIPIYFGSPTIKDWE--- 276
                       .::..||.|||.:|.||:..|||||||.|| .|....:|:..| |:..::|
Human   232 -----------TMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLG-PSRSNYERFL 284

  Fly   277 -PNNKSAIFVNDFQNPQALVEYLNKLADNKKLYNSY 311
             |:  :.|.|:|||:|:.|..||.:|..:...|.||
Human   285 PPD--AFIHVDDFQSPKDLARYLQELDKDHARYLSY 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FucTB	NP_609288.4	Glyco_tran_10_N	38..139	CDD:465336	24/110 (22%)
		Glyco_transf_10	178..>314	CDD:459962	48/139 (35%)
FUT6	NP_000141.1	Glyco_tran_10_N	62..169	CDD:465336	28/125 (22%)
		determines site-specific fucosylation. /evidence=ECO:0000269|PubMed:17604274	73..112		9/38 (24%)
		Glyco_transf_10	185..357	CDD:459962	49/151 (32%)