Protein Alignment Fbp2 and HPGD

DIOPT Version :10

• Sequence 1: NP_523522.1
• Gene: Fbp2 / 34259
• FlyBaseID: FBgn0000640
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_000851.2
• Gene: HPGD / 3248
• HGNCID: 5154
• Length: 266
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 75/272 - (27%)
• Similarity: 126/272 - (46%)
• Gaps: 44/272 - (16%)

  Fly     6 GKNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRME-NVKMMKKLQAINPSVKVVFMQMNLMEKM 69
            ||..:..|:..|||......|:.|..|:..:...:| .|:....|.......|.:|:|.::.::.
Human     5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQ 69

  Fly    70 SIEQAMKKMGQMMGHIDVMINGEGVLLDKDVETTMGMNLTGMIQSTMMAMPYMDKTQMGMGGMVV 134
            .:....:|:....|.:|:::|..||..:|:.|.|:.:||..:|..|.:.:.||.|...|.||:::
Human    70 QLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIII 134

  Fly   135 NMSSVYGLEPAPAFSVYAAAMHGILGFTRSMGDKMIYQKTGVMFMAMCPGLTNSEMIMNLRDNVT 199
            ||||:.||.|.....||.|:.|||:|||||.........:||...|:|||..|:
Human   135 NMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNT----------- 188

  Fly   200 WHHSESMVEAIESAKRQMPEEAAMQMI----HAMEMMK-----------NGSMWIVS----MGQL 245
                 :::|:||.      ||...|.|    |..:|:|           ||.:.::.    .|.:
Human   189 -----AILESIEK------EENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAI 242

  Fly   246 KEVTPT--MHWQ 255
            .::|.:  :|:|
Human   243 MKITTSKGIHFQ 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbp2	NP_523522.1	ADH_SDR_c_like	7..249	CDD:187584	71/261 (27%)
HPGD	NP_000851.2	ADH_SDR_c_like	6..254	CDD:187584	73/269 (27%)