Protein Alignment Fbp2 and HSD17B10

DIOPT Version :10

• Sequence 1: NP_523522.1
• Gene: Fbp2 / 34259
• FlyBaseID: FBgn0000640
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_004484.1
• Gene: HSD17B10 / 3028
• HGNCID: 4800
• Length: 261
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 45/217 - (20%)
• Similarity: 85/217 - (39%)
• Gaps: 37/217 - (17%)

  Fly     6 GKNVVYVGSFSGIGWQMMMQLMQK-------DIKMMGIMHRMENVKMMKKLQAINPSVKVVFMQM 63
            |...|..|..||:|.....:|:.:       |:...|           .:.||.......||...
Human    10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSG-----------GEAQAKKLGNNCVFAPA 63

  Fly    64 NLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLD--------------KDVETTMGMNLTG---M 111
            ::..:..::.|:.......|.:||.:|..|:.:.              :|.:..:.:||.|   :
Human    64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128

  Fly   112 IQSTMMAMPYMDKTQMGMGGMVVNMSSVYGLEPAPAFSVYAAAMHGILGFTRSMGDKMIYQKTGV 176
            |:.....|...:..|.|..|:::|.:||...|.....:.|:|:..||:|.|..:...:  ...|:
Human   129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL--APIGI 191

  Fly   177 MFMAMCPGLTNSEMIMNLRDNV 198
            ..|.:.|||..:.::.:|.:.|
Human   192 RVMTIAPGLFGTPLLTSLPEKV 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbp2	NP_523522.1	ADH_SDR_c_like	7..249	CDD:187584	44/216 (20%)
HSD17B10	NP_004484.1	HSD10-like_SDR_c	9..261	CDD:187629	45/217 (21%)