Protein Alignment Mco1 and LAC1

DIOPT Version :10

• Sequence 1: NP_609287.3
• Gene: Mco1 / 34258
• FlyBaseID: FBgn0032116
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: NP_173252.2
• Gene: LAC1 / 838393
• AraportID: AT1G18140
• Length: 581
• Species: Arabidopsis thaliana
• Alignment Length: 680
• Identity: 170/680 - (25%)
• Similarity: 264/680 - (38%)
• Gaps: 158/680 - (23%)

  Fly   257 TCRYKFVVEWYQTFSKACYDCPRNLTDCSRPHCVMGDGLERSITVVNRMMPGPAIEVCEGDEIVV 321
            |.|:.|.||| :..::.|:                    .:.:..||...|||.:.|.|||.:.:
plant    28 TRRFHFNVEW-KKVTRLCH--------------------TKQLLTVNGQYPGPTVAVHEGDIVEI 71

  Fly   322 DVKNHLLGESTSIHWHGLHQKKTPYMDGVPHITQCPITPHATFRYSFPA-DLSGTHFWHSHTGMQ 385
            .|.|. :..:|:||||||.|.:|.:.||..:||||||....::.|.|.. |..||..||:|...|
plant    72 KVTNR-IAHNTTIHWHGLRQYRTGWADGPAYITQCPIRSKQSYTYRFKVEDQRGTLLWHAHHSWQ 135

  Fly   386 RGDGVFGALIIRKPKTAEPHGGLYDFDLSEHVMIVQDWIHDTGASIFSYHHHSRGDNKPHNLLVN 450
            |. .|:||.|| .|:...|..|.:  ..||..:|:.:|.:|.            .||....::..
plant   136 RA-SVYGAFII-YPRQPYPFSGSH--IQSEIPIILGEWWNDD------------VDNVEKAMMKT 184

  Fly   451 GKGRYYNRIWAEAKQAHRRAEERTTQPVEPLPKSQVDFVQTLPRQARLAKTNTTKLFPVNSRQKR 515
            |.|       |:...|:
plant   185 GAG-------AKVSDAY------------------------------------------------ 194

  Fly   516 GNLNEIPLELVPHQ-----IYTVRRGFRYRFRIINAEYLNCPIVVSIDGHNLTAINSDGFDIEAM 575
             .||.:|..|.|..     ..||..|..|..|||||. ||..:.|::..|.||.:..|....:.:
plant   195 -TLNGLPGPLYPCSTKDTFTATVDAGKTYILRIINAA-LNNELFVAVANHTLTVVEVDAVYTKPV 257

  Fly   576 DVGSIVTYSGERFDFVLNAN-LEVGNYWIRLKGLMDCSEVFTSAFQVAILRYEGAPDEEPTAELS 639
            ...:|:...|:....:|.|: |..|.:.|.....:.....|.::..|..:||.|  ..:|...::
plant   258 HTKAIMIAPGQTTTLLLRADQLSGGEFLIAATPYVTSVFPFNNSTTVGFIRYTG--KTKPENSVN 320

  Fly   640 YGHKAEGIELNVMNRGPGYPDTKTVAEMRALPIYDHVSGIDHDTLKPEADYKFFIYYDFYTKNNP 704
            ...:.....::.:...|...|||...:.             .|::|.....|       |....|
plant   321 TRRRRRLTAMSTVVALPNMLDTKFATKF-------------SDSIKSLGSAK-------YPCKVP 365

  Fly   705 DFHDK------DLYAMDMEMTQ-----QNRLYTPQLNHITLNFPSLALLPS--RSQLK---DSDF 753
            ...||      .|...|..:.|     ..:.:...:|:|:...|.:::|.|  :.|.|   ..||
plant   366 TKIDKRVITTISLNLQDCPLNQTCDGYAGKRFFASMNNISFVRPPISILESYYKKQSKGVFSLDF 430

  Fly   754 CNE-TSLMD-QGIDCRQEFCKCH---HVLQVPLGAVVEMIIVDEGFQYYANHPFHLHGNAFRVMG 813
            ..: .:..| .|:|...|.....   .:.:|..|:.:|::.....|....|||.|:||:.|.|:|
plant   431 PEKPPNRFDFTGVDPVSENMNTEFGTKLFEVEFGSRLEIVFQGTSFLNIENHPLHVHGHNFFVVG 495

  Fly   814 LERLGENVTVEMIKQLDQFNLLKRNLDNPPVKDTVTIPDGGYTIIRFEASNPGYWLFHCHIEFHA 878
              |...|...|  |...::||:     :||.::|..:|.||:..||..|.|||.|..|||:|.|.
plant   496 --RGFGNFDPE--KDPKRYNLV-----DPPERNTFAVPTGGWAAIRINADNPGVWFIHCHLEQHT 551

  Fly   879 EIGMALVFKVGN----DDQMVPVPENFPTC 904
            ..|:|:.|.|.:    ...::|.|.:.|.|
plant   552 SWGLAMGFIVKDGPLPSQTLLPPPHDLPQC 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco1	NP_609287.3	VWC	150..212	CDD:214564
		CuRO_1_tcLCC2_insect_like	293..397	CDD:259927	42/104 (40%)
		CuRO_2_tcLCC_insect_like	415..626	CDD:259951	40/216 (19%)
		CuRO_3_tcLLC2_insect_like	728..897	CDD:259972	54/182 (30%)
LAC1	NP_173252.2	laccase	28..581	CDD:274556	169/678 (25%)