Protein Alignment Mco1 and LAC12

DIOPT Version :10

• Sequence 1: NP_609287.3
• Gene: Mco1 / 34258
• FlyBaseID: FBgn0032116
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: NP_196158.1
• Gene: LAC12 / 830421
• AraportID: AT5G05390
• Length: 565
• Species: Arabidopsis thaliana
• Alignment Length: 641
• Identity: 161/641 - (25%)
• Similarity: 253/641 - (39%)
• Gaps: 153/641 - (23%)

  Fly   297 RSITVVNRMMPGPAIEVCEGDEIVVDVKNHLLGESTSIHWHGLHQKKTPYMDGVPHITQCPITPH 361
            |:...||.|.|||.:||..||.:.|.|.|......| |||||:.|.:|.:.||...:|||||.|.
plant    45 RNAITVNGMFPGPTLEVNNGDTLEVKVHNRARYNIT-IHWHGVRQIRTGWADGPEFVTQCPIRPG 108

  Fly   362 ATFRYSFPAD-LSGTHFWHSHTGMQRGDGVFGALIIRKPKTAEPHGGLYDFDLSEHVMIVQDWIH 425
            .::.|.|... ..||.:||:|:...|.. |:||||                            ||
plant   109 KSYTYRFTIQGQEGTLWWHAHSSWLRAT-VYGALI----------------------------IH 144

  Fly   426 DTGASIFSYHHHSRGDNKPHNLLVNGKGRYYNRIWAEAKQAHRRAEERTTQPVEPLPKSQVDFVQ 490
            .|..|.|.:       .||........|.::|                         .:.||.:.
plant   145 PTPGSSFPF-------PKPDRQTALMLGEWWN-------------------------ANPVDVIN 177

  Fly   491 TLPRQARLAKTNTTKLFPVNSRQKRGNL-NEIPLELVPHQIYTVRRGFRYRFRIINAEYLNCPIV 554
            ...|..  |..|.:..:.:|.:.  |:| |....|.|   :..:..|.....|:|||. ||.|:.
plant   178 QATRTG--AAPNISDAYTINGQP--GDLYNCSTKETV---VVPINSGETSLLRVINAA-LNQPLF 234

  Fly   555 VSIDGHNLTAINSDGFDIEAMDVGSIVTYSGERFDFVLNANLEVGNYWIRLKGLMDCSEV-FTSA 618
            .::..|.||.:.:|...::......::...|:..|.:|.|:.....|:|..:........ |.:.
plant   235 FTVANHKLTVVGADASYLKPFTTKVLMLGPGQTTDVLLTADQPPKRYYIAARAYQSAQNAPFDNT 299

  Fly   619 FQVAILRYEGAPDEEPTAELSYGHKAEGIELNVMNRGPGYPDTKTVA----EMRALPIYDHVSGI 679
            ...|||:|:               |.......:|...|.:.||.||.    :.::|
plant   300 TTTAILQYK---------------KTTTTSKPIMPVLPAFNDTNTVTSFSRKFKSL--------- 340

  Fly   680 DHDTLKPEA--DYKFF---IYYDFYTKNNPDFHDKDLYAMDMEMTQQNRLYTPQLNHITLNFPS- 738
             .:.:.|:.  |..||   :..|...|..|....:.|         ....:|..:|:::...||
plant   341 -RNVVVPKTIDDNLFFTIGLGLDNCPKKFPKSRCQGL---------NGTRFTASMNNVSFVLPSN 395

  Fly   739 LALL---------------PSRSQLK-DSDFCNETSLMDQGIDCRQEFCKCHHVLQVPLGAVVEM 787
            .:||               ||:..:| |....|.:..:.|.:       |...:.::..|:.|::
plant   396 FSLLQAHSNGIPGVFTTDFPSKPPVKFDYTGNNISRALFQPV-------KGTKLYKLKYGSRVQV 453

  Fly   788 IIVDEGFQYYANHPFHLHGNAFRVMGLERLGENVTVEMIKQLDQFNLLKRNLDNPPVKDTVTIPD 852
            ::.|.......|||.||||..|.::| |..| |...:  |...:|||:     :||:::||.:|.
plant   454 VLQDTNIVTSENHPIHLHGYDFYIVG-EGFG-NFNPK--KDTSKFNLV-----DPPLRNTVAVPV 509

  Fly   853 GGYTIIRFEASNPGYWLFHCHIEFHAEIGMALVFKVGND----DQMVPVPENFPTC 904
            .|:.:|||.|.|||.||.|||::.|.:.|:|:.|.|.|.    :.:...|.:.|.|
plant   510 NGWAVIRFVADNPGVWLMHCHLDVHIKWGLAMAFLVDNGVGELETLEAPPHDLPIC 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco1	NP_609287.3	VWC	150..212	CDD:214564
		CuRO_1_tcLCC2_insect_like	293..397	CDD:259927	43/100 (43%)
		CuRO_2_tcLCC_insect_like	415..626	CDD:259951	42/212 (20%)
		CuRO_3_tcLLC2_insect_like	728..897	CDD:259972	55/189 (29%)
LAC12	NP_196158.1	laccase	24..565	CDD:274556	160/639 (25%)