Protein Alignment Mco1 and LAC2

DIOPT Version :10

• Sequence 1: NP_609287.3
• Gene: Mco1 / 34258
• FlyBaseID: FBgn0032116
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: NP_180477.1
• Gene: LAC2 / 817462
• AraportID: AT2G29130
• Length: 573
• Species: Arabidopsis thaliana
• Alignment Length: 669
• Identity: 147/669 - (21%)
• Similarity: 244/669 - (36%)
• Gaps: 204/669 - (30%)

  Fly   297 RSITVVNRMMPGPAIEVCEGDEIVVDVKNHLLGESTSIHWHGLHQKKTPYMDGVPHITQCPITPH 361
            ::|..||...|||.:...|||.:.:.|.|| :..:.||||||:.|.::.:.||..::|||||...
plant    48 KTIVTVNGKFPGPRVTAREGDNLQIKVVNH-VSNNISIHWHGIRQLRSGWADGPSYVTQCPIRMG 111

  Fly   362 ATFRYSFP-ADLSGTHFWHSHTGMQRGDGVFGALIIRKPKTAEPHGGLYDF--DLSEHVMIVQDW 423
            .::.|:|. ....||.:||:|....|.. |:|.||| .||..:|    |.|  ...:..::..:|
plant   112 QSYVYNFTVTGQRGTLWWHAHIQWMRAT-VYGPLII-LPKLHQP----YPFPKPYKQVPILFGEW 170

  Fly   424 IH-DTGASIFSYHHHSRGDNKPHNLLVNG-KGRYYNRIWAEAKQAHRRAEERTTQPVEPLPKSQV 486
            .: |..|.:........|.|.......|| .|..||
plant   171 FNADPQAVVQQALQTGAGPNASDAHTFNGLPGPLYN----------------------------- 206

  Fly   487 DFVQTLPRQARLAKTNTTKLFPVNSRQKRGNLNEIPLELVPHQIYTVRRGFRYRFRIINAEYLNC 551
                       .:..:|.||.                         |:.|..|..|:|||. ||.
plant   207 -----------CSTKDTYKLM-------------------------VKPGKTYLLRLINAA-LND 234

  Fly   552 PIVVSIDGHNLTAINSDGFDIEAMDVGSIVTYSGERFDFVL-------NANL-EVGNYWIRLKGL 608
            .:..:|..|.||.:.:|...::......::...|:..:.:|       ||.. .:...:...:|.
plant   235 ELFFTIANHTLTVVEADACYVKPFQTNIVLLGPGQTTNVLLKTKPIYPNATFYMLARPYFTGQGT 299

  Fly   609 MDCSEVFTSAFQVAILRYEGAPDEEPTAELSYGHKAEGIELNVMNRGPGYPDTKTVAEMRALPIY 673
            :|.:.|      ..||:|:             .|......|:::.  |..|           ||
plant   300 IDNTTV------AGILQYQ-------------HHTKSSKNLSIIK--PSLP-----------PI- 331

  Fly   674 DHVSGIDHDTLKPEADY-KFF--IYYDFYTKNNPDFHDKDLY---AMDMEMTQQNRL-------- 724
                    ::....|:: |.|  :....:..|.|...||..:   .:......:|:.
plant   332 --------NSTSYAANFTKMFRSLASSTFPANVPKVVDKQYFFAIGLGTNPCPKNQTCQGPTNTT 388

  Fly   725 -YTPQLNHITLNFPSLALLPSRSQLKDSDFCNET-------------------------SLMDQG 763
             :...:|:::.      :||:::.|..|.|..::                         :::.:|
plant   389 KFAASINNVSF------ILPNKTSLLQSYFVGKSKNVFMTDFPTAPIIPFNYTGTPPNNTMVSRG 447

  Fly   764 IDCRQEFCKCHHVLQVPLGAVVEMIIVDEGFQYYANHPFHLHGNAFRVMGLERLGENVTVEMIKQ 828
            .          .|:.:.....||:::..........||.||||..|.|:|             :.
plant   448 T----------KVVVLKYKTTVELVLQGTSILGIEAHPIHLHGFNFYVVG-------------QG 489

  Fly   829 LDQFNLLK----RNLDNPPVKDTVTIPDGGYTIIRFEASNPGYWLFHCHIEFHAEIGMALVFKVG 889
            ...||..:    .||.:|..::|:.||.||:..|||.|.|||.||.|||||.|...|:.:.:.|.
plant   490 FGNFNPARDPKHYNLVDPVERNTINIPSGGWVAIRFLADNPGVWLMHCHIEIHLSWGLTMAWVVL 554

  Fly   890 NDD----QMVPVPENFPTC 904
            :.|    :::|.|.:||.|
plant   555 DGDLPNQKLLPPPSDFPKC 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco1	NP_609287.3	VWC	150..212	CDD:214564
		CuRO_1_tcLCC2_insect_like	293..397	CDD:259927	38/100 (38%)
		CuRO_2_tcLCC_insect_like	415..626	CDD:259951	36/220 (16%)
		CuRO_3_tcLLC2_insect_like	728..897	CDD:259972	47/201 (23%)
LAC2	NP_180477.1	laccase	27..573	CDD:274556	146/667 (22%)