Protein Alignment Mco1 and LOC1275582

DIOPT Version :10

• Sequence 1: NP_609287.3
• Gene: Mco1 / 34258
• FlyBaseID: FBgn0032116
• Length: 959
• Species: Drosophila melanogaster
• Sequence 2: XP_314845.5
• Gene: LOC1275582 / 1275582
• VectorBaseID: AGAMI1_005483
• Length: 661
• Species: Anopheles gambiae
• Alignment Length: 716
• Identity: 253/716 - (35%)
• Similarity: 361/716 - (50%)
• Gaps: 111/716 - (15%)

  Fly   218 ARIEELQDNVAESTDDIWTAEWYRNHPCNRDCQVGAEPMTCRYKFVVEWYQTFSKACYDCPR-NL 281
            |..:...:.:.|.::.......:....|.|:|. ..:|..|.:.:.:|.|.....||.||.: |.
Mosquito    23 ANAQSWLNTLLEQSNGTLDVSTFPGEQCLRECD-NTQPRICHFSWTMEHYHVMGPACRDCAKGNH 86

  Fly   282 TDCSRPHCVMGDGLERSITVVNRMMPGPAIEVCEGDEIVVDVKNHLLGESTSIHWHGLHQKKTPY 346
            |||..|.|:..||:||.:..:||.:|||.|.||..|.||||:.|.:.|.|.:||||||||:.|||
Mosquito    87 TDCYHPACITADGVERGVMSLNRKIPGPTISVCRHDLIVVDITNAMAGTSAAIHWHGLHQRATPY 151

  Fly   347 MDGVPHITQCPITPHATFRYSFPADLSGTHFWHSHTGMQRGDGVFGALIIRKPKTAEPHGGLYDF 411
            |||||.||||||....||||:|.|...||.|:|||:|..:.:|.:||||:|:||..:|:|.||.:
Mosquito   152 MDGVPFITQCPIGFGNTFRYAFLATEPGTQFYHSHSGHHKVNGHYGALIVREPKRVDPNGDLYHY 216

  Fly   412 DLSEHVMIVQDWIHDTGASIFSYHHHSRGDNKPHNLLVNGKGRYYNRIWAEAKQAHRRAEERTTQ 476
            |...||::..||:|..| .:|.....|.|...|.|||:||||.|::
Mosquito   217 DTPAHVILGSDWMHIDG-EMFMPGLPSAGGIMPINLLINGKGTYHD------------------- 261

  Fly   477 PVEPLPKSQVDFVQTLPRQARLAKTNTTKLFPVNSRQKRGNLNEIPLELVPHQIYTVRRGFRYRF 541
                 ||                |..||               :.|||     :||||||.|:||
Mosquito   262 -----PK----------------KNETT---------------QTPLE-----VYTVRRGARFRF 285

  Fly   542 RIINAEYLNCPIVVSIDGHNLTAINSDGFDIEAMDVGSIVTYSGERFDFVLNANLEVGNYWIRLK 606
            |.|||....||:.:.|:.|.:..|.||.|.::...|.::|:.||||:||||:||.....||:||:
Mosquito   286 RFINAASHVCPLQLQIEDHMMEVIASDSFHLQPRKVDTLVSTSGERYDFVLDANGVKDTYWVRLR 350

  Fly   607 GLMDCSEVFTSAFQVAILRYEGAP--------DEEPTAELSYGHKAEGIELNVMNRGPGYPDTKT 663
            .|..|:::....|  |:|||...|        ...||.|..:.:.|.....|.....|.:.| ..
Mosquito   351 SLGPCADLQLEQF--AVLRYSTGPFINDAFPTRAPPTYEEPFRNVATANHPNATCGRPEFGD-YC 412

  Fly   664 VAEMRALPIYDHVSGIDHDTLKPEADYKFFIYYDFYTKNNPDFHDKDLYAMDME-MTQQNR---- 723
            :.:.:|   ||    .|.|.:....|::  :.:.||.           |.:..| |.:.||
Mosquito   413 ITDFQA---YD----TDEDVINGVPDHQ--LTFGFYN-----------YPVSFESMFESNRYEHY 457

  Fly   724 -------LYTPQLNHITLNFPSLALLPSRSQLKDSDFCNETSLMDQGIDCRQEFCKCHHVLQVPL 781
                   :....:|:|:|.:|..:||....:::|..||:|.:..|...|  ::.|.|.|.:::.|
Mosquito   458 MNIYGSVMMQGAINNISLAYPPFSLLTQPEKIRDDTFCDEDNRPDSCSD--RQLCTCTHRVKINL 520

  Fly   782 GAVVEMIIVD-EGFQYYANHPFHLHGNAFRVMGLER-LGENVTVEMIKQLDQFNLLKRN-LDNPP 843
            |.:||:.|:| .......||||||||....||.:.: ....:|:|:.:.:.:..||.|| :..||
Mosquito   521 GDIVELYILDLTPSVNDLNHPFHLHGYQMFVMEMSQDRRVPITLEIAQNIARQRLLSRNTVALPP 585

  Fly   844 VKDTVTIPDGGYTIIRFEASNPGYWLFHCHIEFHAEIGMALVFKVGNDDQMVPVPENFPTCGDYN 908
            .||||:||..||..:||.|.|||:||.|||.|:|..:|||||.:||...:||..|.:||.|..|.
Mosquito   586 RKDTVSIPSRGYARVRFRADNPGFWLMHCHYEWHTAVGMALVLQVGETSEMVKAPADFPKCDSYT 650

  Fly   909 P 909
            |
Mosquito   651 P 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco1	NP_609287.3	VWC	150..212	CDD:214564
		CuRO_1_tcLCC2_insect_like	293..397	CDD:259927	60/103 (58%)
		CuRO_2_tcLCC_insect_like	415..626	CDD:259951	68/210 (32%)
		CuRO_3_tcLLC2_insect_like	728..897	CDD:259972	69/171 (40%)
LOC1275582	XP_314845.5	None