Protein Alignment Aldh and MSC7

DIOPT Version :10

• Sequence 1: NP_609285.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_011904.1
• Gene: MSC7 / 856434
• SGDID: S000001081
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 556
• Identity: 154/556 - (27%)
• Similarity: 250/556 - (44%)
• Gaps: 75/556 - (13%)

  Fly     1 MLRVLKTGALLRSQAK--NFAAAVANYSSLPQPQTTPDILYTGVFINNEW--HKSKSGKIF--ET 59
            :::::.|.|...|..|  .|        |||.|:..          .|.|  .:|.|..|:  |.
Yeast    62 LVKIISTPAKCSSSYKPVKF--------SLPAPEAA----------QNNWKGKRSVSTNIWNPEE 108

  Fly    60 IN------PTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERD 118
            .|      |.|.:.:.......:.|||   :....|.|..|.|...|.|.|.|:|..|.|.:..:
Yeast   109 PNFIQCHCPATGQYLGSFPSKTEADID---EMVSKAGKAQSTWGNSDFSRRLRVLASLHDYILNN 170

  Fly   119 QVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTI------PMDGDFF------ 171
            |..:|.:...|:||....:...::...::.::    |..| ||:..      |...:||
Yeast   171 QDLIARVACRDSGKTMLDASMGEILVTLEKIQ----WTIK-HGQRALQPSRRPGPTNFFMKWYKG 230

  Fly   172 TYTRHEPVGVCGQIIPWNFPILMMAWKLGP---ALATGNTIVLKPAEQTSLTALYIAQLVKEA-- 231
            ...|:||:||...|:.||:|...:   |||   ||.|||.||:|.:||...::.:..:|:::.
Yeast   231 AEIRYEPLGVISSIVSWNYPFHNL---LGPIIAALFTGNAIVVKCSEQVVWSSEFFVELIRKCLE 292

  Fly   232 ---GFPEGV--VNVVPGFGTAGAA--LANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELG 289
               ..|:.|  ...:|......:|  ..:|.....:.|.||..|...| |.....:|..|.:|||
Yeast   293 ACDEDPDLVQLCYCLPPTENDDSANYFTSHPGFKHITFIGSQPVAHYI-LKCAAKSLTPVVVELG 356

  Fly   290 GKSPNIIL-SDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNP 353
            ||...|:| |..::|........|.|.:.||.|....|..|..:.||:.|:...:|.....:...
Yeast   357 GKDAFIVLDSAKNLDALSSIIMRGTFQSSGQNCIGIERVIVSKENYDDLVKILNDRMTANPLRQG 421

  Fly   354 FDL----NTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSR---PEGLPGYFVQPTVFADVQD 411
            .|:    |.:.|..:::.:.:::..::|....:||:|:.||||   |:...|::.|||:..||..
Yeast   422 SDIDHLENVDMGAMISDNRFDELEALVKDAVAKGARLLQGGSRFKHPKYPQGHYFQPTLLVDVTP 486

  Fly   412 DMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTY 476
            :|.||:.|:|||:..:::.|..|..::.||::.:||..:||..|:.:.||:...|:.|.|.:|.:
Yeast   487 EMKIAQNEVFGPILVMMKAKNTDHCVQLANSAPFGLGGSVFGADIKECNYVANSLQTGNVAINDF 551

  Fly   477 -NVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSV 511
             .....|.||||...||:|:..||..|......|||
Yeast   552 ATFYVCQLPFGGINGSGYGKFGGEEGLLGLCNAKSV 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_609285.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	145/521 (28%)
MSC7	NP_011904.1	ALDH_F15-22	115..590	CDD:143416	138/485 (28%)