Protein Alignment Aldh and PUT2

DIOPT Version :10

• Sequence 1: NP_609285.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_011902.1
• Gene: PUT2 / 856432
• SGDID: S000001079
• Length: 575
• Species: Saccharomyces cerevisiae
• Alignment Length: 542
• Identity: 146/542 - (26%)
• Similarity: 253/542 - (46%)
• Gaps: 61/542 - (11%)

  Fly     5 LKTGALLRSQAKNFAAAVANYSSLPQPQTTPDILYTG--VFINNEWHKSKSGKIFETINPTT-AE 66
            ||...|||:....|.:     |||..|     ::..|  ::.|||      ..:|...||.. .:
Yeast    41 LKDWDLLRASLMKFKS-----SSLEVP-----LVINGERIYDNNE------RALFPQTNPANHQQ 89

  Fly    67 VIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVY-LASLETLDN 130
            |:|.:..|.::|:..||:||::|.|   .|..:...:|..:..:.|||:.....| :.:...|..
Yeast    90 VLANVTQATEKDVMNAVKAAKDAKK---DWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQ 151

  Fly   131 GKPYSMSYNVDLPTAIKN-LRYFAGWADKNHGKTIPMDGDFFTYTRHE--PV-GVCGQIIPWNFP 191
            ||....: .:|..|.:.: .||:..:|...:.:. |::....|:.:.|  |: |....:.|:||.
Yeast   152 GKNVYQA-EIDCITELSDFFRYYVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFT 214

  Fly   192 ILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPG--FGTAGAALANH 254
            .:.......||| .|||:|.||::..:|:...:..:::|||.|:||:|.:||  .......||:.
Yeast   215 AIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADK 278

  Fly   255 CDVDKVAFTGSTDVGKLI--QLASGNTNLK-----RVTLELGGKSPNIILSDTDMDYAVETAHFG 312
             |...:.|||||:|.|.:  ::.||....|     |:..|.|||:.:::....::.:||.:...|
Yeast   279 -DFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRG 342

  Fly   313 LFFNMGQCCCAGSRTFVEDKIYDEFVE------RSAERAKKRTVGNPF---DLNTEQGPQVNEEQ 368
            .|...||.|.|.||.::.:...:||:.      :|.......|..:|.   :|....||.::|:.
Yeast   343 TFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQS 407

  Fly   369 MEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQL-----I 428
            .:|::.:|:..||.....:..|.:.:...|:||.|||....:.|......|.|||:..:     .
Yeast   408 FDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 472

  Fly   429 RFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLR--AGTVWVN--TYNVLAAQAPFGGYK 489
            .|.::.::|:  |.|:|.|..|:|.||.....|....|:  ||..::|  ....:.:|..|||.:
Yeast   473 EFNEICDIID--NTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535

  Fly   490 MSG-HGRENGEYALSNYTEVKS 510
            ||| ..:..|...||.:..:::
Yeast   536 MSGTDDKAGGPNILSRFVSIRN 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_609285.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	136/513 (27%)
PUT2	NP_011902.1	D1pyr5carbox1	29..574	CDD:273517	146/542 (27%)