Protein Alignment Aldh and ALD2

DIOPT Version :9

• Sequence 1: NP_001260290.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_013893.1
• Gene: ALD2 / 855206
• SGDID: S000004780
• Length: 506
• Species: Saccharomyces cerevisiae
• Alignment Length: 506
• Identity: 231/506 - (45%)
• Similarity: 319/506 - (63%)
• Gaps: 28/506 - (5%)

  Fly    27 SLPQPQTTPDILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFK 91
            ||.||        .|:|||||:..|..||..||:||.|.|.|...|.|:::|:|.||:|||.||
Yeast    16 SLKQP--------LGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAF- 71

  Fly    92 LGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWA 156
             .:.|.:..:.:||..|..|..|:|.:|..||:|||||.||||..:...||...::..|||||.|
Yeast    72 -DNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSA 135

  Fly   157 DK-NHGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLT 220
            || :.|.|||:..:.|.||...|.||..||:|||:|:.|..|||..|||.|||:::||||.|||:
Yeast   136 DKFDKGATIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLS 200

  Fly   221 ALYIAQLVKEAGFPEGVVNVVPGFGT-AGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRV 284
            .||.|.|:|:||||.||||:|||:|: .|.|||:|.|:||::|||||.||..:..|||.:|||.|
Yeast   201 LLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDV 265

  Fly   285 TLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKR- 348
            |||.|||||.::..|.|:|.|::....|:|:|.||.|.|.||.:|:..|||:|||:..|.|||.
Yeast   266 TLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEW 330

  Fly   349 -TVG--NPFDLNTEQGPQVNEEQMEKILGMIKTGKK-------QGAKLVAGGSRPEGLPGYFVQP 403
             ..|  :|||.....||.::..|.::|...|:.||:       |.::...||::     |||:.|
Yeast   331 DVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAK-----GYFIPP 390

  Fly   404 TVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRA 468
            |:|.||.....:.::||||||..:.:|...|:.::.||::.||||:||||||:.||:.....::|
Yeast   391 TIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKA 455

  Fly   469 GTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKN 519
            ||||:|:.|......||||:||||.|||.|:..:..|.:.|:|.:.::..|
Yeast   456 GTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQTKAVHINLSLDN 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	229/497 (46%)
		ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	226/492 (46%)
ALD2	NP_013893.1	ALDH_ALD2-YMR170C	14..502	CDD:143462	230/500 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53964
OrthoFinder	1	1.000	-	-		FOG0000158
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100163
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X158
TreeFam	0	0.000	Not matched by this tool.
	6	5.720