Protein Alignment Aldh and HFD1

DIOPT Version :9

• Sequence 1: NP_001260290.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_013828.1
• Gene: HFD1 / 855137
• SGDID: S000004716
• Length: 532
• Species: Saccharomyces cerevisiae
• Alignment Length: 472
• Identity: 137/472 - (29%)
• Similarity: 212/472 - (44%)
• Gaps: 63/472 - (13%)

  Fly    79 IDIAVQAARNAF-----KL---GSPWRRMDASER----GRLLY-------RLADLMERDQVYLAS 124
            ||..|:.:||.|     ||   .:| |:.|...|    .:|.|       .|.|.|.:| .:...
Yeast    17 IDEIVEISRNFFFEKQLKLSHENNP-RKKDLEFRQLQLKKLYYAVKDHEEELIDAMYKD-FHRNK 79

  Fly   125 LETLDNGKPYSMS---YNVD-LPTAIKNLRYFAGWADKNHGKTIPMDGDFFTYTRHEPV--GVCG 183
            :|::.|.....|:   :.:: ||..||..|..........||||.           |.:  |...
Yeast    80 IESVLNETTKLMNDILHLIEILPKLIKPRRVSDSSPPFMFGKTIV-----------EKISRGSVL 133

  Fly   184 QIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGTAG 248
            .|.|:|||:|:....|..|||.||||||||:|.|..||:.:..|:..||||:|::.||.|.....
Yeast   134 IIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQGAIDET 198

  Fly   249 AALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSD---TDMDYAVETAH 310
            ..|.:....|.:.:|||..||.::...:.. :|....||||||||..|..:   :::..|::...
Yeast   199 TRLLDCGKFDLIFYTGSPRVGSIVAEKAAK-SLTPCVLELGGKSPTFITENFKASNIKIALKRIF 262

  Fly   311 FGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGN----PFDLNTEQGPQVNEEQMEK 371
            ||.|.|.||.|.:.....|...||.:.::..      .:|.|    .||..|:....::|...:|
Yeast   263 FGAFGNSGQICVSPDYLLVHKSIYPKVIKEC------ESVLNEFYPSFDEQTDFTRMIHEPAYKK 321

  Fly   372 ILGMIKTGKKQGAKLVAG----GSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKK 432
            .:..|.:  ..|:|:|..    .|..|.|  ..|.||:..::..|..:.::|.|.||..:|.::.
Yeast   322 AVASINS--TNGSKIVPSKISINSDTEDL--CLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYED 382

  Fly   433 LDEVIER-ANNSEYGLAAAVFTKDLDKANYIVGGLRAG--TVWVNTYNVLAAQAPFGGYKMSGHG 494
            |||.|.: ....:..|...:|:....:.|.|:..||:|  .|.....:|....|||||...||:|
Yeast   383 LDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGIGTSGYG 447

  Fly   495 RENGEYALSNYTEVKSV 511
            ...|.|..:.::..:::
Yeast   448 NYGGYYGFNTFSHERTI 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	137/472 (29%)
		ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	137/472 (29%)
HFD1	NP_013828.1	ALDH-SF	11..466	CDD:416387	137/472 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810