DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aldh and ALDH10A8

DIOPT Version :9

Sequence 1:	NP_001260290.1	Gene:	Aldh / 34256	FlyBaseID:	FBgn0012036	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_565094.1	Gene:	ALDH10A8 / 843831	AraportID:	AT1G74920	Length:	501	Species:	Arabidopsis thaliana

Alignment Length:	501	Identity:	208/501 - (41%)
Similarity:	283/501 - (56%)	Gaps:	33/501 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SLPQPQTTPDILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAF- 90
            ::|.|...       :||:.||.:....|....:||.|.|||.:|..|..||:|:||.|||.|.
plant     2 AIPMPTRQ-------LFIDGEWREPILKKRIPIVNPATEEVIGDIPAATTEDVDVAVNAARRALS 59

  Fly    91 -KLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAG 154
             ..|..|.:...:.|.:.|..:|..:...:..||.||.||.|||        |..|:.::...||
plant    60 RNKGKDWAKAPGAVRAKYLRAIAAKVNERKTDLAKLEALDCGKP--------LDEAVWDMDDVAG 116

  Fly   155 ----WADKNHG--------KTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGN 207
                :||...|        .::||: .|.:|...:|:||.|.|.|||:|:||..||:.|:||.|.
plant   117 CFEFYADLAEGLDAKQKAPVSLPME-SFKSYVLKQPLGVVGLITPWNYPLLMAVWKVAPSLAAGC 180

  Fly   208 TIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGT-AGAALANHCDVDKVAFTGSTDVGKL 271
            |.:|||:|..|:|.|.:|.:.:|.|.|.||:||:.|||: |||.||:|..|||:|||||...|..
plant   181 TAILKPSELASVTCLELADICREVGLPPGVLNVLTGFGSEAGAPLASHPGVDKIAFTGSFATGSK 245

  Fly   272 IQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDE 336
            :..|:... :|.|::|||||||.|:..|.|:|.|.|.|.||.|:..||.|.|.||..|.:.|..|
plant   246 VMTAAAQL-VKPVSMELGGKSPLIVFDDVDLDKAAEWALFGCFWTNGQICSATSRLLVHESIASE 309

  Fly   337 FVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGL-PGYF 400
            |:|:..:.:|...:.:|.:.....||.|::.|.||||..|.|.|.:||.::.||||||.| .|:|
plant   310 FIEKLVKWSKNIKISDPMEEGCRLGPVVSKGQYEKILKFISTAKSEGATILHGGSRPEHLEKGFF 374

  Fly   401 VQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGG 465
            ::||:..||...|.|.|||:||||..:..|...||.||.||:|.|||.|||.:.|.::.:.|...
plant   375 IEPTIITDVTTSMQIWREEVFGPVLCVKTFASEDEAIELANDSHYGLGAAVISNDTERCDRISEA 439

  Fly   466 LRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSV 511
            ..||.||:|.......|||:||.|.||.|||.||:.|.||..||.|
plant   440 FEAGIVWINCSQPCFTQAPWGGVKRSGFGRELGEWGLDNYLSVKQV 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	208/501 (42%)
Aldh	NP_001260290.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	206/494 (42%)
ALDH10A8	NP_565094.1	PLN02467	1..501	CDD:215260	208/501 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153834at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100163
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.720