DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aldh and ALDH3F1

DIOPT Version :9

Sequence 1:	NP_001260290.1	Gene:	Aldh / 34256	FlyBaseID:	FBgn0012036	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_195348.2	Gene:	ALDH3F1 / 829782	AraportID:	AT4G36250	Length:	484	Species:	Arabidopsis thaliana

Alignment Length:	464	Identity:	125/464 - (26%)
Similarity:	209/464 - (45%)	Gaps:	50/464 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 ADKEDIDIAVQAARNAFKLGS----PWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPY 134
            |.||.::.:::..|..|..|.    .||:   ::.|.:...:.|  ..|::..|..:  |.||..
plant     3 AMKETVEESLREMRETFASGRTRSLKWRK---AQIGAIYEMVKD--NEDKICNALFQ--DLGKHS 60

  Fly   135 SMSY----NVDLPTAIKNLRYFAGWADKNHGKT----IPMDGDFFTYTRHEPVGVCGQIIPWNFP 191
            :.::    .|.|.||...:.....||...|.|.    .|..|...:    ||.|....:..||||
plant    61 TEAFRDELGVVLRTATVAINCLDKWAVPKHSKLPLLFYPAKGKVIS----EPYGTVLVLSSWNFP 121

  Fly   192 ILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGTAGAALANHCD 256
            |.:....|..|:|.|||::||.:|.:...:.::|:.: .|......:.|:.|.......|..| .
plant   122 ISLSLDPLIGAIAAGNTVLLKSSELSPNASAFLAKTI-PAYLDTKAIKVIEGGPDVATILLQH-Q 184

  Fly   257 VDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDT---DMDYAVETAHFGLFFNM- 317
            .||:.||||..:|::| :|:...:|..||||||||.|.|:...|   ::...|:....|.:.:.
plant   185 WDKIFFTGSPKIGRII-MAAAAQHLTPVTLELGGKCPTIVDHHTISKNIKSVVKRIAGGKWGSCN 248

  Fly   318 GQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQV----NEEQMEKILGMIKT 378
            ||.|.:.....:|.......::     ..|.|:.:.|..|.::...:    |:..::::..::..
plant   249 GQACISVDYVLIEKSFAPTLID-----MLKPTIKSFFGENPKESGCLSRIANKHHVQRLSRLLSD 308

  Fly   379 GKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNS 443
            .:.| |.:|.|||..|  ...:|:||:..|...|..|..||||||:..:|..:.:.|.|...|..
plant   309 PRVQ-ASIVYGGSIDE--DKLYVEPTILLDPPLDSEIMNEEIFGPILPIITVRDIQESIGIINTK 370

  Fly   444 EYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQ-----APFGGYKMSGHGRENGEYALS 503
            ...||...||.|.:....|:....:|:|   |:|.:..|     .||||...||.||.:|:|:..
plant   371 PKPLAIYAFTNDENLKTRILSETSSGSV---TFNDVMIQYMCDALPFGGVGESGIGRYHGKYSFD 432

  Fly   504 NYTEVKSVI 512
            .::..|:::
plant   433 CFSHEKAIM 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	125/462 (27%)
Aldh	NP_001260290.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	125/464 (27%)
ALDH3F1	NP_195348.2	PLN02203	1..484	CDD:165847	125/464 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810