Protein Alignment Aldh and Aldh3b3

DIOPT Version :10

• Sequence 1: NP_609285.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_082821.2
• Gene: Aldh3b3 / 73458
• MGIID: 1920708
• Length: 479
• Species: Mus musculus
• Alignment Length: 447
• Identity: 123/447 - (27%)
• Similarity: 209/447 - (46%)
• Gaps: 40/447 - (8%)

  Fly    83 VQAARNAFKLG----SPWRRMDASERGRLLY----RLADLMERDQVYLASLETLDNGKPYSMSYN 139
            :|..:.||..|    :.:|.......||.|.    :|.|.::.| :..:..|: |..:.......
Mouse    21 LQRLKEAFNTGKTKTAKFRAEQLQSLGRFLQDNSKQLHDALDGD-LGKSGFES-DMSEIILCENE 83

  Fly   140 VDLPTAIKNLRYFAGWADKNHGKTIPMDGDFFT-----YTRHEPVGVCGQIIPWNFPILMMAWKL 199
            |||  |:|||:   .|.     |..|:..:..|     :.|.||.|:...|.|||:|:.:|...|
Mouse    84 VDL--ALKNLQ---TWM-----KDEPVSTNLLTKLSTAFIRKEPFGLVLIIAPWNYPVNLMIIPL 138

  Fly   200 GPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTG 264
            ..|:|.||.:||||:|.:..|...:|:|:.:. ..:....|:.|.......|..| ..|.:.|||
Mouse   139 VGAIAAGNCVVLKPSEISKNTEKVLAELLPQY-LDQSCFAVMLGGPEETGQLLEH-KFDYIFFTG 201

  Fly   265 STDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFV 329
            |..|||::..|:.. :|..:|||||||:|..:..:.|.........:..:||.||.|.|......
Mouse   202 SPRVGKIVMTAAAK-HLTPITLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYILC 265

  Fly   330 EDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPE 394
            ..::.::.|. :.:.|..|..|:....:...|..:|::..:::.|::..|     ::..||...|
Mouse   266 SQEMQEQLVP-ALQNAITRFYGDNPQTSPNLGRIINQKHFKRLQGLLGCG-----RVAIGGQSDE 324

  Fly   395 GLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKA 459
            |  ..::.|||..|||:...:.:||||||:..|:..:.|||.||..|..|..||...::.:.:..
Mouse   325 G--ERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRSLDEAIEFMNQREKPLALYAYSNNAEVI 387

  Fly   460 NYIVGGLRAGTVWVN---TYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIV 513
            ..::....:|....|   .|..|:: .||||...||.||.:|:::...::..::.::
Mouse   388 KQVLARTSSGGFCGNDGFMYMTLSS-LPFGGVGSSGMGRYHGKFSFDTFSNQRACLL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_609285.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	123/447 (28%)
Aldh3b3	NP_082821.2	ALDH_F3AB	18..460	CDD:143450	123/447 (28%)