DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Aldh and Aldh3b1

DIOPT Version :9

Sequence 1:NP_001260290.1 Gene:Aldh / 34256 FlyBaseID:FBgn0012036 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_080592.2 Gene:Aldh3b1 / 67689 MGIID:1914939 Length:468 Species:Mus musculus


Alignment Length:444 Identity:124/444 - (27%)
Similarity:205/444 - (46%) Gaps:32/444 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    83 VQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGK--------PYSMSY- 138
            :|..|.|||.|   |...|..|...|..|:..:..::..|......|..|        ..::|. 
Mouse     8 LQQLREAFKEG---RTRSAEFRAAQLQGLSHFLRDNKQQLQEALAQDLHKSAFEAEVSEIAISQA 69

  Fly   139 NVDLPTAIKNLRYFAGW-ADKNHGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPA 202
            .|||  |::|||   .| .|:...|.:....| ..:.|.||.|:...|:|||:||.:....|..|
Mouse    70 EVDL--ALRNLR---SWMKDEKVSKNLATQLD-SAFIRKEPFGLVLIIVPWNYPINLTLVPLVGA 128

  Fly   203 LATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTD 267
            :|.||.:||||:|.:..|...:|:::... ..:....||.|.......|..| ..|.:.|||:..
Mouse   129 IAAGNCVVLKPSEISKATEKILAEVLPRY-LDQSCFTVVLGGRQETGQLLEH-KFDYIFFTGNAY 191

  Fly   268 VGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDK 332
            |||:: :|:...:|..:|||||||:|..:..:.|.........:..:||.||.|.|........:
Mouse   192 VGKIV-MAAAAKHLTPITLELGGKNPCYVDDNCDPQIVANRVAWFRYFNAGQTCVAPDYILCSQE 255

  Fly   333 IYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLP 397
            :.:..|. :.:.|..|..|:....:...|..:|::..:::.|::..|     ::..||...||  
Mouse   256 MQERLVP-ALQNAITRFYGDNPQTSPNLGRIINQKHFKRLQGLLGCG-----RVAIGGQSDEG-- 312

  Fly   398 GYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYI 462
            ..::.|||..|||:...:.:||||||:..|:..:.|||.||..|..|..||...|:|.......:
Mouse   313 ERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRSLDEAIEFMNRREKPLALYAFSKRSQVIKQV 377

  Fly   463 VGGLRAGTVWVNT--YNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVK 514
            :....:|....|.  .::..:..||||...||.||.:|:::...::..::.:::
Mouse   378 LARTSSGGFCGNDGFMHMTLSSLPFGGVGTSGMGRYHGKFSFDTFSNQRACLLR 431

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AldhNP_001260290.1 PLN02466 9..512 CDD:215259 124/440 (28%)
ALDH_F1AB_F2_RALDH1 34..514 CDD:143459 124/442 (28%)
Aldh3b1NP_080592.2 ALDH_F3AB 5..447 CDD:143450 124/444 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1012
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.