Protein Alignment Aldh and Aldh9a1

DIOPT Version :10

• Sequence 1: NP_609285.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_071609.2
• Gene: Aldh9a1 / 64040
• RGDID: 68409
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 496
• Identity: 188/496 - (37%)
• Similarity: 295/496 - (59%)
• Gaps: 21/496 - (4%)

  Fly    40 TGVFINNEWHKSKSGKIFETIN---------PTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSP 95
            ||.|:.::....:.|...|.::         |.|...||..:|:.::::::||:.|:.|||:
  Rat     3 TGTFVVSQPLNYRGGARVEPVDASGTEKAFEPATGREIATFKCSGEKEVNLAVENAKAAFKI--- 64

  Fly    96 WRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNH 160
            |.:....||.::|...|.:::..:..:|.:||::|||.. ....:|:.|:.:.|.|:||.|....
  Rat    65 WSKKSGLERCQVLLEAARIIKERRDEIAIMETINNGKSI-FEARLDVDTSWQCLEYYAGLAASMA 128

  Fly   161 GKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIA 225
            |:.|.:.|..|.|||.||:|||..|..||:|..:..||..||||.||.::.||:..|.::||.:|
  Rat   129 GEHIQLPGGSFGYTRREPLGVCLGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLA 193

  Fly   226 QLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTDVG-KLIQLASGNTNLKRVTLELG 289
            ::..:||.|.|:.|||.|....|..|..|.||.||:||||...| |::::|:  ..:|.:|||||
  Rat   194 EIYTKAGAPNGLFNVVQGGAATGQFLCQHRDVAKVSFTGSVPTGMKIMEMAA--KGIKPITLELG 256

  Fly   290 GKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPF 354
            ||||.||.||.:|..||:.|....|...||.||.|:|.||:.:|.|.|.:....:.::..:|:|.
  Rat   257 GKSPLIIFSDCNMKNAVKGALLANFLTQGQVCCNGTRVFVQKEIADAFTKEVVRQTQRIKIGDPL 321

  Fly   355 DLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGG-----SRPEGLPGYFVQPTVFADVQDDMT 414
            ..:|..||.:|...:|::||.:::.|:|||.::.||     ..|:...||::.|.:..:..||||
  Rat   322 LEDTRMGPLINAPHLERVLGFVRSAKEQGATVLCGGEPYAPEDPKLKHGYYMTPCILTNCTDDMT 386

  Fly   415 IAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVL 479
            ..:|||||||..::.|:...||:||||::.:||||.|||:|:.:|:.:...|:|||.::|.|||.
  Rat   387 CVKEEIFGPVMSILTFETEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVS 451

  Fly   480 AAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKNS 520
            ..:.||||||.||.|||||...:..|:::|:|.|::....|
  Rat   452 PVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVES 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_609285.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	186/488 (38%)
Aldh9a1	NP_071609.2	ALDH_F9_TMBADH	31..488	CDD:143409	182/462 (39%)