Protein Alignment Aldh and Aldh1a3

DIOPT Version :10

• Sequence 1: NP_609285.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_444310.3
• Gene: Aldh1a3 / 56847
• MGIID: 1861722
• Length: 512
• Species: Mus musculus
• Alignment Length: 494
• Identity: 304/494 - (61%)
• Similarity: 394/494 - (79%)
• Gaps: 2/494 - (0%)

  Fly    27 SLPQPQTTPDILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFK 91
            :||:|....::.:|.:||||:||:||||:.|.|.||:|.|.|.|::..||.|:|.||:||:.||:
Mouse    19 ALPRPIRNLEVKFTKIFINNDWHESKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQ 83

  Fly    92 LGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWA 156
            .||||||:||..||:||::||||:|||:..||:|||:|.|||:..::.|||...||..|||||||
Mouse    84 RGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWA 148

  Fly   157 DKNHGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTA 221
            ||..|:|||.|.:...:|||||:||||.|.|||||:||:||||.|||..|||:||||||||.|||
Mouse   149 DKIQGRTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTA 213

  Fly   222 LYIAQLVKEAGFPEGVVNVVPGFG-TAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVT 285
            ||:|.|:||.|||.||||:||||| |.|||:::|..::|:||||||:||||::.|:..:||||||
Mouse   214 LYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVREAASRSNLKRVT 278

  Fly   286 LELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTV 350
            ||||||:|.|:.:|.|:|.|||.||.|:|||.||||.|.||.|||:::|.|||.||.|.||||.|
Mouse   279 LELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRPV 343

  Fly   351 GNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTI 415
            |:|||..||||||::::|.:|||.:|::|||:||||..|||..|. .|.|::||||:||.|:|.|
Mouse   344 GDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED-RGLFIKPTVFSDVTDNMRI 407

  Fly   416 AREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLA 480
            |:||||||||.:::||.|:|||:|||:::|||.||||||:||||..:...|.:||||:|.||...
Mouse   408 AKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLAAALESGTVWINCYNAFY 472

  Fly   481 AQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQKN 519
            |||||||:||||:|||.|||||:.|||||:|.:|:.:||
Mouse   473 AQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLEEKN 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_609285.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	298/480 (62%)
Aldh1a3	NP_444310.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		1/2 (50%)
		ALDH_F1AB_F2_RALDH1	26..506	CDD:143459	298/480 (62%)