DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aldh and mctp1

DIOPT Version :9

Sequence 1:	NP_001260290.1	Gene:	Aldh / 34256	FlyBaseID:	FBgn0012036	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_031755510.1	Gene:	mctp1 / 548485	XenbaseID:	XB-GENE-5812768	Length:	919	Species:	Xenopus tropicalis

Alignment Length:	207	Identity:	44/207 - (21%)
Similarity:	69/207 - (33%)	Gaps:	60/207 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 RSAERA--KKRTVGNPFDLNTEQGPQ-VNEEQM--------EKILGMIK----TGKKQGAKLVAG 389
            ||:.:|  ::|:.|.|.     ..|| ...|.:        |.:.|||:    .|:||....|..
Frog    26 RSSGKAGGERRSAGTPC-----HSPQPARREDLAAPAPMLEEMVPGMIRWSGLKGRKQMLDRVFS 85

  Fly   390 GSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTK 454
            .|:|.......|||:........:|...|    |...|.|.|  |.::.:...|:.       .:
Frog    86 SSQPNLCCSESVQPSAPCSSPGSITGTPE----PGSALRRLK--DHLLPQNRGSQQ-------VR 137

  Fly   455 DLDKANYIVGGLRA-------------------GTVWVNTYNVLAAQ-APFGGYKMSGHGRENG- 498
            |.|.......||.|                   ||..::....|:.: :.....|..||.:.|.
Frog   138 DKDGDGQHKSGLSASPTAGKGHRLSHQKSSSLPGTDCLHQLQPLSTKDSDLAQSKPCGHTKNNNN 202

  Fly   499 ------EYALSN 504
                  :|:..|
Frog   203 VGTCTTDYSFPN 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	44/207 (21%)
Aldh	NP_001260290.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	44/207 (21%)
mctp1	XP_031755510.1	C2A_MCTP_PRT	219..339	CDD:176007
		C2B_MCTP_PRT	392..507	CDD:176022
		C2C_MCTP_PRT	546..664	CDD:176023
		PRT_C	<807..>864	CDD:337028
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900