Protein Alignment Aldh and aldh8a1

DIOPT Version :9

• Sequence 1: NP_001260290.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001004540.1
• Gene: aldh8a1 / 447801
• ZFINID: ZDB-GENE-040912-3
• Length: 487
• Species: Danio rerio
• Alignment Length: 470
• Identity: 189/470 - (40%)
• Similarity: 277/470 - (58%)
• Gaps: 16/470 - (3%)

  Fly    55 KIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQ 119
            |:.::.:|:|.||..::..:..|:::.||:||:.||   ..|.....::|.::|.:||||:|...
Zfish    23 KLIDSFDPSTGEVYCKVPDSGAEEVNAAVRAAKEAF---PDWSAKSPADRSKVLNKLADLIEARL 84

  Fly   120 VYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMDG-DFFTYTRHEPVGVCG 183
            ......|:.|.||..:.:.|||:|.:..|.|:||.....:......||. ....||...||||.|
Zfish    85 EEFVQAESKDQGKTITFARNVDIPRSAYNFRFFASSVLHHTNDCSQMDHMGCLNYTIRCPVGVAG 149

  Fly   184 QIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGT-- 246
            .|.|||.|:.::.||:.||:|||||:|.||:|.||:||..:.||::|||||.||||:|  |||
Zfish   150 LISPWNLPLYLLTWKIAPAVATGNTVVAKPSEMTSVTAWMMCQLLEEAGFPPGVVNIV--FGTGP 212

  Fly   247 -AGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAH 310
             ||.||.:|.||..::|||||...:||...|. .:.|:::||||||:|.||.:|.||:..:.|..
Zfish   213 RAGDALVSHPDVPLISFTGSTATARLITERSA-PHCKKLSLELGGKNPAIIFADADMEQCISTTV 276

  Fly   311 FGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGM 375
            ...|.|.|:.|...||.|||..:|.||:.|..|..::...|.|.|.:.:.|..:::|.::|:.|.
Zfish   277 RSSFSNQGEICLCTSRIFVERSVYPEFLTRFVEATRRWKTGVPSDPSNDNGALISKEHLQKVKGY 341

  Fly   376 IKTGKKQGAKLVAG-GSRPEGLP-----GYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLD 434
            |.....:||::..| |.....||     |||:.||:.:.|:|...:.:|||||||..:..|.:.:
Zfish   342 ITLALAEGAQVHCGEGVDKLALPQQNIGGYFMLPTIISGVKDSSALMQEEIFGPVTCVTPFDEEE 406

  Fly   435 EVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGE 499
            |||.||||..|||:|.|:::|:.:.:.:...|:||.||.|.:.|.....||||.|.||.|||.|:
Zfish   407 EVISRANNVRYGLSATVWSRDVGRVHRVARKLQAGLVWTNCWLVRDLNLPFGGMKHSGIGREGGK 471

  Fly   500 YALSNYTEVKSVIVK 514
            .:...:||||||.||
Zfish   472 DSYHFFTEVKSVTVK 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	186/466 (40%)
		ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	187/468 (40%)
aldh8a1	NP_001004540.1	ALDH_F8_HMSADH	27..485	CDD:143412	186/463 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810