Protein Alignment Aldh and Aldh3a1

DIOPT Version :10

• Sequence 1: NP_609285.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_114178.1
• Gene: Aldh3a1 / 25375
• RGDID: 2088
• Length: 453
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 136/466 - (29%)
• Similarity: 208/466 - (44%)
• Gaps: 68/466 - (14%)

  Fly    79 IDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETL------DNGKPYSMS 137
            |...|:.||.||..|         :...|.:|:..|....::...:|:::      |.||....|
  Rat     4 ISDTVKRAREAFNSG---------KTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTS 59

  Fly   138 YN-------VDLPTAIKNLRYFAGWA-DKNHGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILM 194
            |.       .:|.|.||.|   ..|| |:...||.....|.. |...||:||...|..||:|..:
  Rat    60 YYEEVAHVLEELDTTIKEL---PDWAEDEPVAKTRQTQQDDL-YIHSEPLGVVLVIGAWNYPFNL 120

  Fly   195 MAWKLGPALATGNTIVLKPAE----QTSLTALYIAQ-------LVKEAGFPEGVVNVVPGFGTAG 248
            ....:..|:|.||.::|||:|    ...|.|..|.|       ||.:.|.||....:...|
  Rat   121 TIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQYMDQNLYLVVKGGVPETTELLKERF---- 181

  Fly   249 AALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGL 313
                     |.:.:||||.|||:: :|:...:|..||||||||||..:..|.|:|.|.....:|.
  Rat   182 ---------DHIMYTGSTAVGKIV-MAAAAKHLTPVTLELGGKSPCYVDKDCDLDVACRRIAWGK 236

  Fly   314 FFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKT 378
            |.|.||.|.|......:..|.::.||: .:::.|...|.....:.:.|..:|:...:::.|:|
  Rat   237 FMNSGQTCVAPDYILCDPSIQNQIVEK-LKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLI-- 298

  Fly   379 GKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNS 443
               ...|:..||:..:.  ..::.||:..||.....:.:|||||||..::..:.|:|.|:..|..
  Rat   299 ---DNQKVAHGGTWDQS--SRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLEEAIQFINQR 358

  Fly   444 EYGLAAAVFT---KDLDK--ANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALS 503
            |..||..||:   |.:.|  |....||:.|..|.|   ::.....||||...||.|..:|:.:..
  Rat   359 EKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIV---HITVPTLPFGGVGNSGMGAYHGKKSFE 420

  Fly   504 NYTEVKSVIVK 514
            .::..:|.:||
  Rat   421 TFSHRRSCLVK 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_609285.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	134/464 (29%)
Aldh3a1	NP_114178.1	ALDH_F3AB	5..447	CDD:143450	135/465 (29%)