Protein Alignment Aldh and ALDH3B1

DIOPT Version :9

• Sequence 1: NP_001260290.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_000685.1
• Gene: ALDH3B1 / 221
• HGNCID: 410
• Length: 468
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 119/442 - (26%)
• Similarity: 201/442 - (45%)
• Gaps: 36/442 - (8%)

  Fly    87 RNAFKLG----SPWRRMDASERGRLLYR----LADLMERDQVYLASLETLDNGKPYSMSYNVDLP 143
            |.||..|    :.:|.......||.|..    |.|.:.:| ::.::.|:..:....|..   ::.
Human    12 REAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQD-LHKSAFESEVSEVAISQG---EVT 72

  Fly   144 TAIKNLRYFAGWADKNHGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNT 208
            .|::|||  |...|:...|.:....| ..:.|.||.|:...|.|||:|:.:....|..|||.||.
Human    73 LALRNLR--AWMKDERVPKNLATQLD-SAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNC 134

  Fly   209 IVLKPAEQT----SLTALYIAQLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTDVG 269
            :||||:|.:    .:.|..:.|.|.::.|.     ||.|.......|..| ..|.:.||||..||
Human   135 VVLKPSEISKNVEKILAEVLPQYVDQSCFA-----VVLGGPQETGQLLEH-RFDYIFFTGSPRVG 193

  Fly   270 KLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIY 334
            |::..|:.. :|..||||||||:|..:..:.|.........:..:||.||.|.|........::.
Human   194 KIVMTAAAK-HLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQ 257

  Fly   335 DEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGY 399
            :..:. :.:....|..|:....:...|..:|::|.:::..::..|     ::..||...|.  ..
Human   258 ERLLP-ALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCG-----RVAIGGQSDES--DR 314

  Fly   400 FVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVG 464
            ::.|||..|||:...:.:||||||:..::..:.|||.||..|..|..||...|:........::.
Human   315 YIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVLT 379

  Fly   465 GLRAGTVWVNT--YNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVK 514
            ...:|....|.  .::..|..||||...||.||.:|:::...::..::.:::
Human   380 QTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRACLLR 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	119/438 (27%)
		ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	119/440 (27%)
ALDH3B1	NP_000685.1	ALDH_F3AB	6..447	CDD:143450	119/442 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810