Protein Alignment Aldh and ALDH3A1

DIOPT Version :9

• Sequence 1: NP_001260290.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_005256579.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 104/364 - (28%)
• Similarity: 166/364 - (45%)
• Gaps: 54/364 - (14%)

  Fly   161 GKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAE----QTSLTA 221
            |:..|:    ..|..|.|..||                     :.||::||||:|    ..||.|
Human   229 GRAEPL----VKYPGHRPGSVC---------------------SAGNSVVLKPSELSENMASLLA 268

  Fly   222 LYIAQLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTL 286
            ..|.|.:.:..:|  |:|  .|.......|...  .|.:.:||||.|||:|..|:.. :|..|||
Human   269 TIIPQYLDKDLYP--VIN--GGVPETTELLKER--FDHILYTGSTGVGKIIMTAAAK-HLTPVTL 326

  Fly   287 ELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVG 351
            |||||||..:..:.|:|.|.....:|.|.|.||.|.|......:..|.::.||: .:::.|...|
Human   327 ELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEK-LKKSLKEFYG 390

  Fly   352 NPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIA 416
            .....:.:.|..::....::::|:|     :|.|:..||:.....  .::.||:..||.....:.
Human   391 EDAKKSRDYGRIISARHFQRVMGLI-----EGQKVAYGGTGDAAT--RYIAPTILTDVDPQSPVM 448

  Fly   417 REEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDK------ANYIVGGLRAGTVWVNT 475
            :|||||||..::..:.|:|.|:..|..|..||..:|:.: ||      |....||:.|..|.|
Human   449 QEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSN-DKVIKKMIAETSSGGVAANDVIV-- 510

  Fly   476 YNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVK 514
             ::.....||||...||.|..:|:.:...::..:|.:|:
Human   511 -HITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVR 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	103/360 (29%)
		ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	103/362 (28%)
ALDH3A1	XP_005256579.1	ALDH-SF	<248..564	CDD:299846	97/320 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810