Protein Alignment Aldh and alh-5

DIOPT Version :10

• Sequence 1: NP_609285.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_503545.1
• Gene: alh-5 / 178680
• WormBaseID: WBGene00000111
• Length: 437
• Species: Caenorhabditis elegans
• Alignment Length: 443
• Identity: 128/443 - (28%)
• Similarity: 206/443 - (46%)
• Gaps: 24/443 - (5%)

  Fly    83 VQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIK 147
            |:|.|..|..|:   ...|..|...|.:|..|:|.::..|..:...|..:.:.::..::|..:::
 Worm     7 VEAQRAYFNTGA---TKPAEFRKEQLLQLKKLIEENRAALTEVVWKDLRRRHEVTEPMELGGSLE 68

  Fly   148 NLRYFA----GWADKNHGK----TIPMDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALA 204
            .:.|:.    .|....:.:    |:|.|.   .|...:|.||...|.|||:|:.|:...:.|::|
 Worm    69 EIAYYLKNLDDWMKPTYVEPTVATLPTDK---PYIVKDPKGVVLVISPWNYPVSMVLLPMIPSIA 130

  Fly   205 TGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTDVG 269
            .|||||:||:|.:..||:...:|:.:...|:.|..|..|.......|...  .|.:.:||...|.
 Worm   131 AGNTIVIKPSELSENTAILFEKLIPKYFDPKYVTIVNGGIPETTELLKER--FDHIIYTGCPPVA 193

  Fly   270 KLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIY 334
            |:| :|:...:|..||||||||.|.::..|.|::.:.:....|.:.|.||.|.|.....|.....
 Worm   194 KII-MAAAAKHLTPVTLELGGKCPVVVEDDADIEISAQRIARGKWLNCGQTCLAPDYILVSSATK 257

  Fly   335 DEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGY 399
            .:|| .:.::..|...|.....:.:....:|:...::|..::...|   ..::||..........
 Worm   258 PKFV-AAIQKCLKEFYGGNAKESKDYSRVINQRHFDRISALLDESK---GVVLAGNEESRDRSDR 318

  Fly   400 FVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVG 464
            |:.|||. ||:.......:||||||..:|..|.|.|.|:..|..|..|||.:||||..|....:.
 Worm   319 FIPPTVL-DVEKTDPFMHDEIFGPVLPIITVKNLCESIDFINKGEKPLAAYIFTKDEAKVQRFLN 382

  Fly   465 GLRAGTVWVN--TYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKV 515
            ...:|.|.||  ..:|.....||||..:||.||..|::....:|..|||:.:|
 Worm   383 ETTSGGVTVNDVIMHVAVITLPFGGVGVSGMGRYRGKFGFDTFTHEKSVLQRV 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_609285.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	127/440 (29%)
alh-5	NP_503545.1	ALDH_F3-13-14_CALDH-like	6..433	CDD:143406	127/439 (29%)