DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Aldh and AgaP_AGAP009944

DIOPT Version :9

Sequence 1:	NP_001260290.1	Gene:	Aldh / 34256	FlyBaseID:	FBgn0012036	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_319075.3	Gene:	AgaP_AGAP009944 / 1279360	VectorBaseID:	AGAP009944	Length:	510	Species:	Anopheles gambiae

Alignment Length:	505	Identity:	276/505 - (54%)
Similarity:	362/505 - (71%)	Gaps:	24/505 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 DILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMD 100
            :|.||.:||||::..:.|||.|.|:||:|.:.:|:|...||.|:::||:||:.||...|.||:||
Mosquito     7 EIKYTKIFINNQFVDAVSGKTFPTVNPSTGKKLADIAEGDKADVELAVKAAKTAFVRTSTWRQMD 71

  Fly   101 ASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIP 165
            ||.||.||::|:.|||||...|||||:||||||:..:. .|:..:||..||:||.|||..|.|||
Mosquito    72 ASARGALLWKLSTLMERDANVLASLESLDNGKPFPNAM-YDVQGSIKTFRYYAGLADKVGGDTIP 135

  Fly   166 MDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKE 230
            .||..|||||.|||||.|||||||:|:.|:|||.|||||.|.|||:||||||.|||||:|.|.||
Mosquito   136 SDGPHFTYTRKEPVGVVGQIIPWNYPLAMLAWKWGPALAAGCTIVIKPAEQTPLTALYMAALSKE 200

  Fly   231 AGFPEGVVNVVPGFG-TAGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPN 294
            ||||:||:|||||:| |||.|:::|.::.|||||||.:|||:|..|:..:|||:|:||||||||.
Mosquito   201 AGFPDGVINVVPGYGPTAGGAISSHPEIRKVAFTGSVEVGKIIMAAAATSNLKKVSLELGGKSPL 265

  Fly   295 IILSDTD---------------------MDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFV 338
            :|..|.:                     :|.|...|:..:|.|.||||.|.:||||.:.|||:||
Mosquito   266 VICEDANGKRGDSLIKISIAFVIFFISTVDQAAMIAYMAVFENQGQCCIAATRTFVHESIYDQFV 330

  Fly   339 ERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQP 403
            ::::|.||.|.|||||...|..|||:::.|.:||||.|:.|:|:|||||.|| :..|..|||::|
Mosquito   331 QKASELAKARKVGNPFTEGTVHGPQIDDTQYKKILGYIEVGQKEGAKLVTGG-KTVGNEGYFIEP 394

  Fly   404 TVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRA 468
            |:||:|.||||||:||||||||.:|:::.|||.||||||:.:||||.:.|.|::||......:.|
Mosquito   395 TIFANVTDDMTIAKEEIFGPVQSIIKYRTLDEAIERANNTSFGLAAGIVTNDINKALTFSHAVEA 459

  Fly   469 GTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVKVAQK 518
            |:||||||..:..||||||||.||.|||.|:.:|..|.|.|||.:::..|
Mosquito   460 GSVWVNTYLAVVNQAPFGGYKQSGIGRELGKDSLEGYLETKSVSIRLPAK 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	274/497 (55%)
Aldh	NP_001260290.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	275/499 (55%)
AgaP_AGAP009944	XP_319075.3	PLN02466	3..508	CDD:215259	275/502 (55%)
AgaP_AGAP009944	XP_319075.3	ALDH-SF	5..505	CDD:299846	275/499 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53964
OrthoDB	1	1.010	-	-		D153834at2759
OrthoFinder	1	1.000	-	-		FOG0000158
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X158
TreeFam	0	0.000	Not matched by this tool.
	6	5.830