Protein Alignment Aldh and Aldh3a1

DIOPT Version :9

• Sequence 1: NP_001260290.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001318041.1
• Gene: Aldh3a1 / 11670
• MGIID: 1353451
• Length: 454
• Species: Mus musculus
• Alignment Length: 468
• Identity: 128/468 - (27%)
• Similarity: 207/468 - (44%)
• Gaps: 70/468 - (14%)

  Fly    78 DIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNV-- 140
            :|...|..||:||..|         :...|.:|:..|....::...:|:.:......::..|.
Mouse     3 NISSIVNRARDAFNSG---------KTRPLQFRVEQLEALQRMINENLKGISKALASNLRKNEWT 58

  Fly   141 -----------DLPTAIKNLRYFAGWA-DKNHGKTIPMDGDFFTYTRHEPVGVCGQIIPWNFPIL 193
                       ::...||.|   :.|| |:...||.....|.. |...||:||...|..||:|..
Mouse    59 SYYEEVAHVLDEIDFTIKGL---SDWAEDEPVAKTRQTQEDDL-YIHSEPLGVVLVIGAWNYPFN 119

  Fly   194 MMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKE-----------AGFPEGVVNVVPGFGTA 247
            :....:..|:|.||.:||||:|.:...|..::.|:.:           .|.||....:...|
Mouse   120 LTIQPMVGAIAAGNAVVLKPSEVSDHMADLLSTLIPQYMDKDLYPVIKGGVPETTELLKEKF--- 181

  Fly   248 GAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFG 312
                      |.:.:||||.|||:: :|:...:|..||||||||||..:..|.|:|.|.....:|
Mouse   182 ----------DHIMYTGSTAVGKIV-MAAAAKHLTPVTLELGGKSPCYVDKDCDLDVACRRIAWG 235

  Fly   313 LFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIK 377
            .|.|.||.|.|......:..|.:|.||: .:::.|...|.....:.:.|..:|:...::::.:|
Mouse   236 KFMNSGQTCVAPDYILCDPSIQNEIVEK-LKKSLKDFYGEDAKQSHDYGRIINDRHFQRVINLI- 298

  Fly   378 TGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANN 442
                ...|:..||:..:  |..::.||:..||.....:.:|||||||..::..:.|||.|:..|.
Mouse   299 ----DSKKVAHGGTWDQ--PSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLDEAIKFINQ 357

  Fly   443 SEYGLAAAVFTKDLDK------ANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYA 501
            .|..||..||:.: ||      |....||:.|..|.|   ::.....||||...||.|..:|:.:
Mouse   358 REKPLALYVFSNN-DKVIKKMIAETSSGGVTANDVIV---HITVPTLPFGGVGNSGMGAYHGKKS 418

  Fly   502 LSNYTEVKSVIVK 514
            ...::..:|.:|:
Mouse   419 FETFSHRRSCLVR 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	127/464 (27%)
		ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	127/466 (27%)
Aldh3a1	NP_001318041.1	ALDH_F3AB	5..447	CDD:143450	127/466 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810