Protein Alignment Aldh and Aldh7a1

DIOPT Version :9

• Sequence 1: NP_001260290.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_613066.2
• Gene: Aldh7a1 / 110695
• MGIID: 108186
• Length: 539
• Species: Mus musculus
• Alignment Length: 483
• Identity: 144/483 - (29%)
• Similarity: 227/483 - (46%)
• Gaps: 37/483 - (7%)

  Fly    41 GVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERG 105
            ||: |..|  ...|::..|..|...|.||.::.|..:|.:..:..|:.|:.:   |..:.|.:||
Mouse    53 GVY-NGSW--GGRGEVITTYCPANNEPIARVRQASLKDYEETIGKAKKAWNI---WADIPAPKRG 111

  Fly   106 RLLYRLADLMERDQVYLASLETLDNGKPY-----SMSYNVDLPTAIKNLRYFAGWADKNHGKTIP 165
            .::.::.|........|..|.:|:.||..     .:...||:      ..|.||.:....|.|:|
Mouse   112 EIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDV------CDYAAGLSRMIGGPTLP 170

  Fly   166 MDGDFFTYTR-HEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTAL----YIA 225
            .:........ ..|:|:.|.|..:|||:.:..|....||.|||..:.|.|..|||.::    .||
Mouse   171 SERPGHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIA 235

  Fly   226 QLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTDVGK----LIQLASGNTNLKRVTL 286
            |::::...|..:.::|.|....|..:|....|:.::|||||.|||    ::|...|.:     .|
Mouse   236 QVLEDNLLPGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKS-----LL 295

  Fly   287 ELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVG 351
            ||||.:..|...|.|:...|.:..|......||.|....|.|:.:.|::|.|:|......:..||
Mouse   296 ELGGNNAIIAFEDADLSLVVPSVLFAAVGTAGQRCTTVRRLFLHESIHNEVVDRLRSAYSQIRVG 360

  Fly   352 NPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIA 416
            ||:|.|...||...::.:...:..::..||||..:|.||...:. ||.:|:||:...:..|..|.
Mouse   361 NPWDPNILYGPLHTKQAVSMFVRAVEEAKKQGGTVVYGGKVMDH-PGNYVEPTIVTGLAHDAPIV 424

  Fly   417 REEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVG--GLRAGTVWVN--TYN 477
            .:|.|.|:..:.:|:..:||.|..|..:.||::::|||||.:....:|  |...|.|.||  |..
Mouse   425 HQETFAPILYVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSG 489

  Fly   478 VLAAQAPFGGYKMSGHGRENGEYALSNY 505
            .....| |||.|.:|.|||:|..|...|
Mouse   490 AEIGGA-FGGEKHTGGGRESGSDAWKQY 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	144/483 (30%)
		ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	144/483 (30%)
Aldh7a1	NP_613066.2	ALDH_F7_AASADH	53..527	CDD:143448	144/483 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810