Protein Alignment Aldh and aldh1l1

DIOPT Version :9

• Sequence 1: NP_001260290.1
• Gene: Aldh / 34256
• FlyBaseID: FBgn0012036
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001185701.1
• Gene: aldh1l1 / 100526683
• ZFINID: ZDB-GENE-100519-4
• Length: 903
• Species: Danio rerio
• Alignment Length: 480
• Identity: 224/480 - (46%)
• Similarity: 329/480 - (68%)
• Gaps: 9/480 - (1%)

  Fly    42 VFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGR 106
            :|||.|:..::.||.:::||||..:.|.::..|...|::.||.||:.||:.|. |.:|:..:||:
Zfish   425 LFINGEFVDAEGGKTYKSINPTDGQAICDVSLAQISDVEKAVAAAKEAFEEGE-WGKMNPRDRGK 488

  Fly   107 LLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMD---- 167
            |||:||||||:.|..||::|::|:|..|:::....:..:|:..||||||.||..|.|||::
Zfish   489 LLYKLADLMEQHQEELATIESIDSGAVYTLALKTHIGMSIQTFRYFAGWCDKIQGCTIPINQARP 553

  Fly   168 GDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAG 232
            ....|:|:.||:||||.:||||:|::|:|||....||.|||:|||||:.|.||||..|:|...|.
Zfish   554 NRNLTFTKKEPIGVCGIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTALKFAELTALAK 618

  Fly   233 FPEGVVNVVPGFGT-AGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNII 296
            ||:||||::||.|: .|..|::|.||.|:.|||||::||.|..:...:|:|:|:||||||||.||
Zfish   619 FPKGVVNILPGSGSLVGQRLSDHPDVRKLGFTGSTEIGKHIMKSCAVSNVKKVSLELGGKSPLII 683

  Fly   297 LSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQG 361
            .:|.|:|.||......:|||.|:.|.|..|.|:|:.|:|.|:||.....:|..:|:|.|.:|:.|
Zfish   684 FNDCDLDKAVRMGMSSVFFNKGENCIAAGRLFIEESIHDIFLERVVSEIRKMKIGDPLDRSTDHG 748

  Fly   362 PQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQ 426
            ||.::..::|::...:.|.|:|||||.||.:.| .||:|.:||||.||||.|.||.||.||||..
Zfish   749 PQNHKAHLDKLVEYCEKGVKEGAKLVCGGKQVE-RPGFFFEPTVFTDVQDHMYIAVEESFGPVMI 812

  Fly   427 LIRFK--KLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYK 489
            :.:|.  ::|:|::|||.:|:|||:.|||:|:.||.|:...|:||||::||||.....|||||:|
Zfish   813 ISKFSNGEVDKVLQRANATEFGLASGVFTRDISKALYVSEKLQAGTVFINTYNKTDVAAPFGGFK 877

  Fly   490 MSGHGRENGEYALSNYTEVKSVIVK 514
            .||.|::.|:.||:.|.:.|.|.|:
Zfish   878 QSGFGKDLGQEALNEYLKTKCVTVE 902

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	222/476 (47%)
		ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	223/478 (47%)
aldh1l1	NP_001185701.1	Fmt	1..306	CDD:223301
		FMT_core_FDH_N	1..203	CDD:187716
		FDH_Hydrolase_C	206..307	CDD:187731
		ALDH_F1L_FTFDH	418..903	CDD:143458	224/480 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153834at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920