Protein Alignment CG3748 and LEMD1

DIOPT Version :10

• Sequence 1: NP_609281.1
• Gene: CG3748 / 34252
• FlyBaseID: FBgn0032110
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: XP_011508462.1
• Gene: LEMD1 / 93273
• HGNCID: 18725
• Length: 209
• Species: Homo sapiens
• Alignment Length: 188
• Identity: 36/188 - (19%)
• Similarity: 57/188 - (30%)
• Gaps: 71/188 - (37%)

  Fly    15 DIQRLTDAQLSTMCKSHGLILGPITFQNRRMAERKL----------------------------- 50
            |::.|:|.:|....:..|...|||....|::.|:||
Human     3 DVKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDDS 67

  Fly    51 ---------HIAMITERAKYRAHQQFALECNMKTQVPPAQQNYGLVDVLPQNYYQPMPPQTYWPS 106
                     :|.:.||::|       .|:.|...::...|:..    |.|...|........||.
Human    68 EELNIILQGNIILSTEKSK-------KLKKNPVFEIQEQQEEI----VEPNTDYNDSKMIIRWPE 121

  Fly   107 PGTNLRSPP-------PPS----WNTQN----------RRERTDPVLEPRQYVSWRQQ 143
            ..|..|...       .||    |..:.          .:|| |...|.:...|||::
Human   122 ASTTKRKAVDTYCLDYKPSKGRRWAARAPSTRITYGTITKER-DYCAEDQTIESWREE 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3748	NP_609281.1	LEM	14..57	CDD:128813	13/79 (16%)
LEMD1	XP_011508462.1	LEM_LAP2_LEMD1	3..44	CDD:240587	12/40 (30%)