Protein Alignment Eaat1 and gltP

DIOPT Version :10

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_418501.1
• Gene: gltP / 948591
• ECOCYCID: EG10405
• Length: 437
• Species: Escherichia coli
• Alignment Length: 492
• Identity: 129/492 - (26%)
• Similarity: 220/492 - (44%)
• Gaps: 97/492 - (19%)

  Fly    10 KFKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVS 74
            ||....|   :..|.|:|:.:|..:.:  .:.:.:|  ..:..:|..|:||:.::|.::||:::|
E. coli     5 KFSLAWQ---ILFAMVLGILLGSYLHY--HSDSRDW--LVVNLLSPAGDIFIHLIKMIVVPIVIS 62

  Fly    75 SITSAIGGL-DLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASK 138
            ::...|.|: |.....:|..:.|.|:.|.|..|:||||.|....:||.|..:.:..|..|.|
E. coli    63 TLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIILGITLANVFQPGAGVDMSQLATVDISK--- 124

  Fly   139 VLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIYENT---------SISPAQPMENWEFKSAQREGS 194
                                    :|..||..:::         |:.|...:       |.....
E. coli   125 ------------------------YQSTTEAVQSSSHGIMGTILSLVPTNIV-------ASMAKG 158

  Fly   195 NVLGLVMFSVILGTTIGRM----REKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKII 255
            .:|.::.|||:.|..:..:    ||.   |...|.::||.|..:|..|:..:|:||..|
E. coli   159 EMLPIIFFSVLFGLGLSSLPATHREP---LVTVFRSISETMFKVTHMVMRYAPVGVFAL------ 214

  Fly   256 EMESIAATIQSLG----WYFITVMIGLFLHGFGTIAVIFF----LG-TRRL----PYRYIAKLSQ 307
                ||.|:.:.|    |....::  |.:|    .|::||    || ..||    .:..|..|..
E. coli   215 ----IAVTVANFGFSSLWPLAKLV--LLVH----FAILFFALVVLGIVARLCGLSVWILIRILKD 269

  Fly   308 VLATAFGTGSSSATMPLTIKCLDNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMS 372
            .|..|:.|.||.:.:|..|:.::..|....:|.||:|.|.:.|:||:.||:::||:||||...:.
E. coli   270 ELILAYSTASSESVLPRIIEKMEAYGAPVSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID 334

  Fly   373 YSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVM 437
            .|....:.:.:|....|.|.||:|....|.::..|.:||:..:.::.|..||.:||..||.:||:
E. coli   335 LSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVV 399

  Fly   438 CDALGTILV---NHLSKNDLASVDRLNAEPHELLELG 471
            .:||..:::   .|       ..||..|..:|...||
E. coli   400 GNALAVLVIAKWEH-------KFDRKKALAYEREVLG 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	GltP	20..448	CDD:440912	119/457 (26%)
gltP	NP_418501.1	gltP	1..437	CDD:183075	129/492 (26%)