Protein Alignment Eaat1 and Slc1a4

DIOPT Version :10

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_061349.3
• Gene: Slc1a4 / 55963
• MGIID: 2135601
• Length: 532
• Species: Mus musculus
• Alignment Length: 493
• Identity: 180/493 - (36%)
• Similarity: 301/493 - (61%)
• Gaps: 29/493 - (5%)

  Fly     4 PKQDGGKFK---AFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLK 65
            |:...||.:   :|.:.:.|.:.||.||.||..:|..::..  :.::.:|.|::||||:.||||:
Mouse    25 PETAMGKSQRCASFFRRHALVLLTVSGVLVGAGMGAALRGL--QLTRTQITYLAFPGEMLLRMLR 87

  Fly    66 CLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQT 130
            .:|:||:|.|:.|....||.|...::...|:.|:.:||:||..|.:.|...::||.||:.:::.:
Mouse    88 MIILPLVVCSLVSGAASLDASSLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGAGAQTLQSSS 152

  Fly   131 ESIDKA-----SKVLTPDTLMDLVRNMFTDNIIQSTMFQHRTE---IYENTSISPAQ----PMEN 183
            ..::.:     ||. |.|:.:||:||:|..|::.:......|:   :..|||.....    |:
Mouse   153 LGLENSGPPPVSKE-TVDSFLDLLRNLFPSNLVVAAFTTSATDYTVVTHNTSSGNVTKEKIPV-- 214

  Fly   184 WEFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAF 248
                ....||.|:||||:|:::||..:.::..:|:.|..||.:.:||.|.:.||::|..|:|:.|
Mouse   215 ----VTDVEGMNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIGIMF 275

  Fly   249 LIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAF 313
            ||.:||:||:.|...:.|||.|....|:|..:||...:.:::|..||:.|:.::..|....||||
Mouse   276 LIGSKIVEMKDIVMLVTSLGKYIFASMLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLLTPFATAF 340

  Fly   314 GTGSSSATMPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGT 377
            .|.|||||:|..:||: :|.|:|.|::||::|:|||:||||.|:::.|||:||||...:..:.|.
Mouse   341 ATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQ 405

  Fly   378 IVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALG 442
            |..:.:||||:|:||||:|..|::|:.::|:.:||...|:|||:||||::||..|.:||..||||
Mouse   406 IFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLSLILAVDWIVDRTTTVVNVEGDALG 470

  Fly   443 TILVNHLSKNDLASVDRLNAEPHEL-LELGPNGHEMKE 479
            ..::|||::.   .|.:...|..|: :|..||....:|
Mouse   471 AGILNHLNQK---VVKKGEQELQEVKVEAIPNSKSEEE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	GltP	20..448	CDD:440912	166/440 (38%)
Slc1a4	NP_061349.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		1/3 (33%)
		GltP	52..496	CDD:440912	168/455 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	495..532		4/11 (36%)