Protein Alignment Eaat1 and slc1a6

DIOPT Version :9

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_009304076.1
• Gene: slc1a6 / 559270
• ZFINID: ZDB-GENE-071004-45
• Length: 576
• Species: Danio rerio
• Alignment Length: 509
• Identity: 224/509 - (44%)
• Similarity: 321/509 - (63%)
• Gaps: 47/509 - (9%)

  Fly     2 TRPKQDG---GKFKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRM 63
            :|.|..|   ...|.|::.|...:.||..|.:|..:||.::  ....|.|::.|.|||||:.:||
Zfish    57 SRRKMGGITRNSVKTFLRRNAFVIFTVAAVALGVALGFALR--PHNLSIRQVKYFSFPGELLMRM 119

  Fly    64 LKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVET 128
            |:.|::||:|||:.:.|..||...|.|:..|||.||.|||:.||.:||.:|..::||:|::  ::
Zfish   120 LQMLVLPLIVSSLVTGISSLDSKASGKMGIRAIVYYMVTTLIAVFIGIVMVIIIKPGKGSR--DS 182

  Fly   129 QTESIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIYENT-------------------- 173
            ...|......|...|..:||:||||..|::::...|::| :|:.|
Zfish   183 PVASSGSIEPVQAADAFLDLIRNMFPPNLVEACFKQYKT-LYKKTVLTKNVTIVVNATENVNSTD 246

  Fly   174 -----SISPA-----QPMENWEFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLS 228
                 :.||.     :.:|.....|....|.|.||||:||:..|..||.|:::||.|:|||..|:
Zfish   247 LSQVSNFSPVLQTIQETVEEAVPVSGSSNGVNALGLVVFSMCFGLVIGNMKQQGQALRDFFDCLN 311

  Fly   229 EAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLG 293
            ||:|.:.:.:||.:|:|:.||||.||:||:.:|.....||.|.::|::||.:||...:.::||:.
Zfish   312 EAIMRLVAIIIWYAPVGILFLIAGKIVEMKDLAQVGGQLGMYTVSVIVGLLIHGLLVLPLLFFVV 376

  Fly   294 TRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALY 357
            |::.|:.:||.|.|.|.||.||.|||||:|:|.:|| :|..:|.||||||:||||||||||||||
Zfish   377 TKKNPFTFIAGLLQALITALGTSSSSATLPITFRCLEENNHVDKRVTRFVLPVGATINMDGTALY 441

  Fly   358 EAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIA 422
            |||||:||||..:|..:||.|:.:|||||||||||||||||||||||:||.:|||..:|::||||
Zfish   442 EAVAAIFIAQVNDMDLNFGQILTISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIA 506

  Fly   423 VDWLLDRFRTTINVMCDALGTILVNHLSKNDLA--------SVDRLNAEPHELL 468
            |||.|||.|||.||:.|:.|..:|.|||:.:|.        ||...|.:|::|:
Zfish   507 VDWFLDRLRTTTNVLGDSFGAGIVEHLSRQELQNQDVEISNSVIEENEKPYQLI 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	SDF	20..449	CDD:395299	209/459 (46%)
slc1a6	XP_009304076.1	SDF	78..533	CDD:278787	209/459 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	397	1.000	Domainoid score	I716
eggNOG	1	0.900	-	-		E1_COG1301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H21055
Inparanoid	1	1.050	415	1.000	Inparanoid score	I1797
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm24560
orthoMCL	1	0.900	-	-		OOG6_100309
Panther	1	1.100	-	-	O	PTHR11958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.880