Protein Alignment Eaat1 and slc1a3b

DIOPT Version :10

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001177232.1
• Gene: slc1a3b / 556181
• ZFINID: ZDB-GENE-090708-3
• Length: 537
• Species: Danio rerio
• Alignment Length: 487
• Identity: 222/487 - (45%)
• Similarity: 313/487 - (64%)
• Gaps: 30/487 - (6%)

  Fly    12 KAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSI 76
            |.|::.|...:.|:..|..|..:||.:::.  :.|.||:.|.|||||:.:|||:.|::||||||:
Zfish    42 KGFLRRNAFVLFTIGAVVFGITLGFALRSY--KMSYREVKYFSFPGELLMRMLQMLVLPLLVSSL 104

  Fly    77 TSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASKVLT 141
            .:.:..||...|.|:..||:.||..||..||.:||.:|..:.||:|:|...|:.:.|::.|..
Zfish   105 ITGMAALDSRASGKMGMRAVIYYMTTTFIAVFIGIIMVLIIHPGKGSKDEFTKQQKIEQVSPA-- 167

  Fly   142 PDTLMDLVRNMFTDNIIQSTMFQHRTE---------------IYENTSISPAQPMENWEFKSAQR 191
             |..:||:||||..|::|:...|.:|:               |:..|:.:.....|.....|...
Zfish   168 -DAFLDLIRNMFPPNLVQACTQQFKTQYGKRIIHVKMIVNDSIFNLTNATQEIAQEEVIPLSGTT 231

  Fly   192 EGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIE 256
            .|.|.||||:||:..|..||.|:|:||.|:|||.:|:||:|.:.:.::|.:|:|:.||||.||:|
Zfish   232 NGVNALGLVVFSMCFGLIIGNMKEQGQALRDFFDSLNEAIMRLVAIIMWYAPIGILFLIAGKIVE 296

  Fly   257 MESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSAT 321
            |:.|.|....||.|.:||:|||.:||...:..::|:.||:.|:.:|..|.|.|.||.||.|||||
Zfish   297 MDDITAMGGQLGMYTVTVIIGLMIHGIIILPTLYFVITRKNPFIFITGLLQALITALGTSSSSAT 361

  Fly   322 MPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITA 385
            :|:|.||| :|..:|.||||||:||||||||||||||||:||:||||...|..:||.|:.:||||
Zfish   362 LPITFKCLEENNKVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNMEMNFGQIITISITA 426

  Fly   386 TAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLS 450
            |||||||||||||||||||:||.:|||...|::|||||||.|||.|||.||:.|::|..::..||
Zfish   427 TAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSIGAGIIEFLS 491

  Fly   451 KNDLASVDRLNAEPHELLELGPNGHEMKEXRQ 482
            |::|...|         :|||.:..|..| ::
Zfish   492 KDELQGGD---------VELGSSVLEENELKK 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	GltP	20..448	CDD:440912	209/443 (47%)
slc1a3b	NP_001177232.1	GltP	46..487	CDD:440912	210/445 (47%)