Protein Alignment Eaat1 and slc1a3a

DIOPT Version :9

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_997805.1
• Gene: slc1a3a / 323439
• ZFINID: ZDB-GENE-030131-2159
• Length: 537
• Species: Danio rerio
• Alignment Length: 528
• Identity: 237/528 - (44%)
• Similarity: 332/528 - (62%)
• Gaps: 52/528 - (9%)

  Fly    12 KAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSI 76
            |.|...|...:.||..|.||.::||.::  ..:.|.||:.|.|||||:.:|||:.|::||||||:
Zfish    42 KGFFMRNAFVILTVAAVIVGIILGFGLR--PYKMSYREVKYFSFPGELLMRMLQMLVLPLLVSSL 104

  Fly    77 TSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASKVLT 141
            .:.:..||...|.|:..||:.||..|||.||.:||.:|..:.||:|:|...|:.|.|::.|..
Zfish   105 ITGMAALDSRASGKMGVRAVVYYTTTTIIAVFIGIVMVLIIHPGKGSKDEFTKHEKIEQVSPA-- 167

  Fly   142 PDTLMDLVRNMFTDNIIQSTMFQHRTEIYENTSISPAQPMENWEF------KSAQRE-------- 192
             |..:||:||||..|::|:...|.:|: |....::....:.:..|      :..:||
Zfish   168 -DAFLDLIRNMFPPNLVQACTQQFKTQ-YGKRVVTVKVLVNDTVFSLNNGTQELKREEVIPVLGT 230

  Fly   193 --GSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKII 255
              |.|.||||:||:..|..||.|:|:||.|:|||..|:||:|.:.:.::|.:|||:.||||.||:
Zfish   231 VNGINALGLVVFSMCFGLIIGNMKEQGQPLRDFFDCLNEAIMRLVAIIMWYAPLGIMFLIAGKIV 295

  Fly   256 EMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSA 320
            ||:.::.....||.|.|||:|||.:|....:.:::||.||:.|:.:||.|.|.|.||.||.||||
Zfish   296 EMDDLSEMGGQLGMYTITVIIGLLIHAVIVLPLLYFLVTRKNPFVFIAGLLQALITALGTSSSSA 360

  Fly   321 TMPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSIT 384
            |:|:|.||| :|.|:|.||||||:||||||||||||||||:||:||||..:|..:||.|:.:|||
Zfish   361 TLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNDMEMNFGEILTISIT 425

  Fly   385 ATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHL 449
            ||||||||||||||||||||:||.:|||...|::|||||||.|||.|||.||:.|::|..:|.||
Zfish   426 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSIGAGIVEHL 490

  Fly   450 SKNDLASVDRLNAEPHELLELGPNGHEMKEXRQSSLGAYNRKRXVDMSRLWACFHILPSNDSDSD 514
            |:::|.|:|         .|:|.:..|..|.::|                    :.|.|.:|:||
Zfish   491 SRHELRSID---------AEIGNSVLEENETKKS--------------------YQLISQESESD 526

  Fly   515 DYDDDDEE 522
            :....|.|
Zfish   527 NAKIPDSE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	SDF	20..449	CDD:395299	216/445 (49%)
slc1a3a	NP_997805.1	SDF	50..490	CDD:278787	216/445 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	397	1.000	Domainoid score	I716
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	415	1.000	Inparanoid score	I1797
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm24560
orthoMCL	1	0.900	-	-		OOG6_100309
Panther	1	1.100	-	-	O	PTHR11958
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5013
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.010