Protein Alignment Eaat1 and Slc1a2

DIOPT Version :10

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_063139305.1
• Gene: Slc1a2 / 29482
• RGDID: 3697
• Length: 579
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 208/509 - (40%)
• Similarity: 305/509 - (59%)
• Gaps: 45/509 - (8%)

  Fly    17 ENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIG 81
            :|:|...||.||.:|.:.|.::: .........:|.|:|||:|.:||||.||:||::||:.:.:.
  Rat    49 KNLLLSLTVFGVILGAVCGGLLR-LAAPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLS 112

  Fly    82 GLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASKVLTPDTLM 146
            |||...|.::.|||:.||..|||.|.:||:.||..:.||...  ::.|.....|..:|.:.|..:
  Rat   113 GLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPK--LKKQLGPGKKNDEVSSLDAFL 175

  Fly   147 DLVRNMFTDNIIQSTMFQHRTEIYENTSISPAQPMEN---------------------------W 184
            ||:||:|.:|::|: .||....:.:...::|.....|                           .
  Rat   176 DLIRNLFPENLVQA-CFQQIQTVTKKVLVAPPSEEANTTKAVISLLNETMNEAPEETKIVIKKGL 239

  Fly   185 EFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFL 249
            |||    :|.|||||:.|.:..|..:|:|.|:.:|:.:||..|:|.:|.:...::|.||||:|.|
  Rat   240 EFK----DGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACL 300

  Fly   250 IAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFG 314
            |..|||.::.:....:.||.|.|||::||.:||...:.:|:|:.||:.|:.:.|.:.|...||.|
  Rat   301 ICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALG 365

  Fly   315 TGSSSATMPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTI 378
            |.||:.|:|:|.:|| ||:|||.||||||:|||||||||||||||||||:||||...:....|.|
  Rat   366 TASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQI 430

  Fly   379 VAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGT 443
            |.||:|||.||||||.||.||||||:::|..|||..:|:||::||||||||.||::||:.|:.|.
  Rat   431 VTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGA 495

  Fly   444 ILVNHLSKNDLASVDRLNAEPHELLEL--------GPNGHEMKEXRQSSLGAYN 489
            .:|.||||::|.::|..: ..||.:|:        ....|.... .|....|:|
  Rat   496 GIVYHLSKSELDTIDSQH-RMHEDIEMTKTQSIYDDTKNHRESNSNQCVYAAHN 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	GltP	20..448	CDD:440912	194/455 (43%)
Slc1a2	XP_063139305.1	None