Protein Alignment Eaat1 and Slc1a6

DIOPT Version :9

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_006513485.3
• Gene: Slc1a6 / 20513
• MGIID: 1096331
• Length: 602
• Species: Mus musculus
• Alignment Length: 500
• Identity: 214/500 - (42%)
• Similarity: 304/500 - (60%)
• Gaps: 66/500 - (13%)

  Fly    12 KAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSI 76
            :.|::.|...:.||..|.:|..:.|.::  ..:.|.|:|.|.|||||:.:|||:.|::||:|||:
Mouse    75 RRFLRRNAFILLTVSAVIIGVSLAFALR--PYQLSYRQIKYFSFPGELLMRMLQMLVLPLIVSSL 137

  Fly    77 TSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASK--- 138
            .:.:..||...:.::..||..||.|||:.||.:||.:||.:.||:|:|      |.:.:..:
Mouse   138 VTGMASLDNKATGRMGMRAAVYYMVTTVIAVFIGILMVTIIHPGKGSK------EGLHREGRIET 196

  Fly   139 VLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIYE-----------------NTSISPAQPMEN--- 183
            |.|.|..||||||||..|::::...|.:|: |.                 ..|:||...:||
Mouse   197 VPTADAFMDLVRNMFPPNLVEACFKQFKTQ-YSTRVVTRTIVRTDNGSELGASMSPTSSVENETS 260

  Fly   184 ---------------WEFKS-----AQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLS 228
                           ..|:.     ....|.|.||||:|||..|..||.|:.||::|:|||.:|:
Mouse   261 ILENVTRALGTLQEVISFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLN 325

  Fly   229 EAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLG 293
            ||:|.:...:||.:|:|:.||||.||:|||.:|.....||.|.:||::|||||..|.:.:|:||.
Mouse   326 EAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLV 390

  Fly   294 TRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALY 357
            |.|.|:.:|..:.|.|.||.||.|||||:|:|.:|| :.:|:|.|:||||:|||||:||||||||
Mouse   391 THRNPFPFIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALY 455

  Fly   358 EAVAALFIAQYREMSYSFGTIVAV-------------SITATAASIGAAGIPQAGLVTMVMVLDT 409
            ||:||:||||......:.|.|..:             ||||||||:||||||||||||||:||.:
Mouse   456 EALAAIFIAQVNNYELNLGQITTISLSSRIPDSLPVCSITATAASVGAAGIPQAGLVTMVIVLTS 520

  Fly   410 VGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDL 454
            |||..:|::|||||||.|||.||..||:.|::|..::.|||:.:|
Mouse   521 VGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQREL 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	SDF	20..449	CDD:395299	208/485 (43%)
Slc1a6	XP_006513485.3	SDF	83..560	CDD:366058	208/485 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	389	1.000	Domainoid score	I784
eggNOG	1	0.900	-	-		E1_COG1301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H21055
Inparanoid	1	1.050	402	1.000	Inparanoid score	I1910
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm43973
orthoMCL	1	0.900	-	-		OOG6_100309
Panther	1	1.100	-	-	O	PTHR11958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.880