Protein Alignment Eaat1 and Slc1a2

DIOPT Version :10

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001070982.1
• Gene: Slc1a2 / 20511
• MGIID: 101931
• Length: 572
• Species: Mus musculus
• Alignment Length: 511
• Identity: 207/511 - (40%)
• Similarity: 304/511 - (59%)
• Gaps: 50/511 - (9%)

  Fly    17 ENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIG 81
            :|:|...||.||.:|.:.|.:::.:: ......:|.|:|||:|.:||||.||:||::||:.:.:.
Mouse    43 KNLLLSLTVFGVILGAVCGGLLRLAS-PIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLS 106

  Fly    82 GLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASKVLTPDTLM 146
            |||...|.::.|||:.||..|||.|.:||:.||..:.||...  ::.|.....|..:|.:.|..:
Mouse   107 GLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPK--LKKQLGPGKKNDEVSSLDAFL 169

  Fly   147 DLVRNMFTDNIIQSTMFQHRTEIYENTSISPAQPMEN---------------------------W 184
            ||:||:|.:|::|: .||....:.:...::|.....|                           .
Mouse   170 DLIRNLFPENLVQA-CFQQIQTVTKKVLVAPPSEEANTTKAVISMLNETMNEAPEETKIVIKKGL 233

  Fly   185 EFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFL 249
            |||    :|.|||||:.|.:..|..:|:|.|:.:|:.:||..|:|.:|.:...::|.||||:|.|
Mouse   234 EFK----DGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACL 294

  Fly   250 IAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFG 314
            |..|||.::.:....:.||.|.|||::||.:||...:.:|:|:.||:.|:.:.|.:.|...||.|
Mouse   295 ICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALG 359

  Fly   315 TGSSSATMPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTI 378
            |.||:.|:|:|.:|| ||:|||.||||||:|||||||||||||||||||:||||...:....|.|
Mouse   360 TASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQI 424

  Fly   379 VAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGT 443
            |.||:|||.||||||.||.||||||:::|..|||..:|:||::||||||||.||::||:.|:.|.
Mouse   425 VTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGA 489

  Fly   444 ILVNHLSKNDLASVDRLNAEPHELLE----------LGPNGHEMKEXRQSSLGAYN 489
            .:|.||||::|.::|    ..|.:.|          .....|.... .|....|:|
Mouse   490 GIVYHLSKSELDTID----SQHRMQEDIEMTKTQSIYDDKNHRESNSNQCVYAAHN 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	GltP	20..448	CDD:440912	194/455 (43%)
Slc1a2	NP_001070982.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		SDF	46..495	CDD:425646	194/456 (43%)