Protein Alignment Eaat1 and glt-4

DIOPT Version :9

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_509075.3
• Gene: glt-4 / 188744
• WormBaseID: WBGene00001622
• Length: 499
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 206/492 - (41%)
• Similarity: 304/492 - (61%)
• Gaps: 39/492 - (7%)

  Fly    16 QENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAI 80
            :||:|.:.||:||.||..:||.:::.:..||||.:.|:.|||::|::|||.||:|:::|||.:::
 Worm     6 KENLLLLFTVLGVVVGIGLGFSLRDPSKAWSKRHLSYLRFPGDLFVQMLKMLILPMIMSSIITSL 70

  Fly    81 GGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASKVLTP--- 142
            ..||...:.::...::.||.:||..||.|||.||:.::||:.     |.|...|....|.|.
 Worm    71 ASLDSGTAGRLGMVSMIYYTLTTFFAVFLGIVLVSVIKPGKW-----TTTNIEDLVGHVKTTPCV 130

  Fly   143 ----DTLMDLVRNMFTDNIIQST---------MFQHRTEIYEN--TSISPAQPMENWEF-KSAQR 191
                ||::||:::.|.:|:|::|         .|...|||...  .::||.|..:..|. :....
 Worm   131 ATAVDTIIDLMKSCFPENLIEATFRSQKICLKFFNGTTEIPPEIAMTMSPEQRAQFTEVPEKIVS 195

  Fly   192 EGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIE 256
            :|.|:||||:|||.||..||.:.|.|:.:::||.:|....|.:..|||..||:|:.|||||:|:.
 Worm   196 DGMNILGLVVFSVALGIVIGVIGEDGKPMKNFFKSLEACSMKLIGWVIIYSPVGITFLIAAQIVG 260

  Fly   257 MESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSAT 321
            |:.....:..|..|.|||::||.:|.|..|.::..:..||.|.:::..::|.|.||..|.|||||
 Worm   261 MKDPGQELHRLMGYVITVILGLLIHAFVVIPLLCVVLARRNPIKFVGGMAQALLTALATSSSSAT 325

  Fly   322 MPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITA 385
            :||:|||. :|..:||||||||:|:|||||||||||||||||::|:|......|.|.:|.||:||
 Worm   326 LPLSIKCCEENNKVDPRVTRFVLPLGATINMDGTALYEAVAAIYISQCYGNDLSLGEVVLVSLTA 390

  Fly   386 TAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILV---- 446
            |.||||||||||||:|||:|||..:||......||..||::|||.|||:||..|::.|.::
 Worm   391 TLASIGAAGIPQAGIVTMIMVLIAIGLPTNLFILIFPVDFMLDRLRTTVNVHGDSIATAVIERLC 455

  Fly   447 --------NHLSKNDLA-SVDRLNAEPH-ELLELGPN 473
                    :||..||.. |:...||.|. :.:.:|.|
 Worm   456 EDQLQKGGHHLDTNDQGYSMLSTNASPDPKRITIGNN 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	SDF	20..449	CDD:395299	194/460 (42%)
glt-4	NP_509075.3	SDF	10..454	CDD:278787	194/448 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158393
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100309
Panther	1	1.100	-	-	LDO	PTHR11958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.760