Protein Alignment Eaat1 and glt-5

DIOPT Version :9

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_496094.1
• Gene: glt-5 / 174530
• WormBaseID: WBGene00001623
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 198/499 - (39%)
• Similarity: 312/499 - (62%)
• Gaps: 23/499 - (4%)

  Fly     5 KQDGGKFKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIV 69
            |:...::.:::.:|:|.:.|:.|:.:|.:||.:::  |.:.|...|.|:.||||:|:.|||.:::
 Worm     6 KKSVSRWTSWLTKNMLLLMTMAGIVMGVIIGGVLR--TADPSPDVIRYVGFPGELFMNMLKAMVL 68

  Fly    70 PLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESID 134
            ||:.:||.|.:..||...|.::.:||:.||.:||..||||||.:|:.::||......:...:...
 Worm    69 PLIAASIVSGLSQLDGKTSGRLGSRAVMYYAITTTHAVILGIIVVSIIQPGDPTIKQKMGYDKEG 133

  Fly   135 KASKVLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIYENTSISPAQPMENWEFKSAQREGSNVLGL 199
            :|:.|......:||.||.|.:||:::|..|.:|. |.|.:.|.....|  ...:...:|.||||:
 Worm   134 EAANVSAAQKFLDLFRNAFPENIMRATFSQVQTN-YINQTHSNGATHE--VLHTGYVDGMNVLGI 195

  Fly   200 VMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATI 264
            ::|.:::|..:.|:.|:.:.|.:.|..|...:..:...::|:.|:|:..|||.|::|:..:..|.
 Worm   196 IVFCIVMGLVVSRIGEEAKALANLFHALDVVITRMVMLIMWLGPIGIPSLIAQKMLEVSDLWLTA 260

  Fly   265 QSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCL 329
            :.||.:..||::||.:..|.|:.:|:|:|||..||.::..|.|.:.||.||.||:|::|:|.:||
 Worm   261 RMLGLFVFTVILGLAIQAFITLPLIYFIGTRHNPYTFLKGLGQAIMTALGTSSSAASLPVTFRCL 325

  Fly   330 DNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAG 394
            :.:|||||||:||:||||.:||||||||||.|::||||...:..|.|.||.||||||.||||||.
 Worm   326 NKLGIDPRVTKFVLPVGAMVNMDGTALYEATASIFIAQMNGLELSIGQIVTVSITATLASIGAAS 390

  Fly   395 IPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDR 459
            ||.||||||::||..:||...|:|||:||||.|||.||::||:.||||...|:|:      ..|.
 Worm   391 IPSAGLVTMLIVLTALGLPANDISLILAVDWFLDRLRTSVNVIGDALGCGFVHHI------CADH 449

  Fly   460 LNAE------PHELLEL-GPNGHEM-KEXRQSSLGAYNRKRXVD 495
            |||:      .|.::|. |.|..|: || .|.:    |.:: ::
 Worm   450 LNADVAEAEKNHAVVEAHGVNFDELEKECEQEN----NNQKQIE 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	SDF	20..449	CDD:395299	182/428 (43%)
glt-5	NP_496094.1	SDF	21..442	CDD:278787	181/425 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm14639
orthoMCL	1	0.900	-	-		OOG6_100309
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.730