Protein Alignment Eaat1 and Eaat2

DIOPT Version :10

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_555593.4
• Gene: Eaat2 / 1278051
• VectorBaseID: AGAMI1_004694
• Length: 566
• Species: Anopheles gambiae
• Alignment Length: 509
• Identity: 168/509 - (33%)
• Similarity: 282/509 - (55%)
• Gaps: 58/509 - (11%)

  Fly     5 KQDGGK----------------FKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYI 53
            ||:.|:                :...:.:|.|.:.|:.||.:|.:|||..: ..| .|...:|.|
Mosquito    16 KQEAGQLSREDTLLKMADHRSSWSRVLADNKLILITLSGVLLGVIIGFTFR-PLG-LSSDSLMLI 78

  Fly    54 SFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLR 118
            ::|||:|:|:||.:|:||:::|:.|....|:..::.|||.|...|:..|::...|||..|...:.
Mosquito    79 AYPGELFMRVLKLMILPLVIASLISGSSSLNAKLNGKIALRTFVYFLTTSLLNAILGTTLALIIH 143

  Fly   119 PGQGAKIVETQTE------SIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIY------- 170
            ||.........||      .:.||..|...|:::||.||:|.|||.|:.:.|..| :|
Mosquito   144 PGNPTAESAAHTELLRDTTPLSKAKTVSLMDSVLDLGRNIFPDNIFQAALQQAHT-VYVPKELPG 207

  Fly   171 ---ENTSIS------------PAQPMENWEFKSAQ----------REGSNVLGLVMFSVILGTTI 210
               .:|.:|            .|..:...|:.:.|          |.|:|.||:|.|.::.||.:
Mosquito   208 MVGNDTELSHTSAPVMASSSASASSVNLMEWSAEQNVEWIRIVEYRSGTNSLGIVFFCLVFGTLL 272

  Fly   211 GRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVM 275
            |.:..||.::..||:.:.:.:|.:.:.|:|::|:|::.:||.||:.::.:...:..|.|:..|:.
Mosquito   273 GTIGRKGYVVVQFFSAIFDVIMKMVTGVMWLTPIGISSVIAGKILSVDDVGFVMTQLAWFIFTIA 337

  Fly   276 IGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCL-DNMGIDPRVT 339
            :|:||:.:..:..|:|:..|:.|:|:...|.|.:.|.|.|.|::|.:|||.:|: :.:.||.|:|
Mosquito   338 LGVFLYQWIILQAIYFVFLRKNPFRFYLGLVQPILTGFATASTAAALPLTFRCMNERLKIDSRIT 402

  Fly   340 RFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMV 404
            |||:|:|..||||||||:.|||::||||...||.:.|.:|.|.:|:||||:.:|.||.|.||.::
Mosquito   403 RFVLPIGCNINMDGTALFIAVASIFIAQMSNMSLNVGQVVTVVLTSTAASMSSASIPSAALVLLL 467

  Fly   405 MVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVD 458
            :.|..:.....:.:|:.|:||.:||.|||.|::.|.....:|.|||:|:|...|
Mosquito   468 IALSAIDAPINNATLLFAIDWFVDRIRTTNNLLGDCYAAAVVEHLSRNELKISD 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	GltP	20..448	CDD:440912	158/466 (34%)
Eaat2	XP_555593.4	None